- Lewis Chodosh, University of Pennsylvania
Novel molecular regulators of the tumor necrosis factor-related apoptosis inducing ligand (TRAIL) pathway in breast cancer cells were identified, suggesting their role in combination with TRAIL as potential therapeutic targets for breast cancer.
Mammographic texture resemblance (MTR) is validated as an independent risk factor for breast cancer, following two study cohorts indicating elevated risk despite differences in x-ray technology, population demographics, follow up time and geography.
There is little evidence of an association between low-dose aspirin usage and breast cancer-specific survival in a cohort of newly diagnosed breast cancer patients from the UK Clinical Practice Research Datalink.
Smith and Schiavon review adjuvant endocrine therapy for hormone receptor-positive early breast cancer, discussing how extended therapy for selected patients with tamoxifen or an aromatase inhibitor (AI) further reduces risk of relapse.
Rare breast phyllodes possess many characteristics of mesenchymal stem cells (MSCs), with aldehyde dehydrogenase and disialoganglioside serving as novel markers for these malignant phyllode tumors.
Receptor-interacting protein kinase 2 (RIP2) is a pro-metastasis kinase overexpressed in triple negative breast cancer (TNBC); targeting RIP2 may improve outcomes in advanced breast cancer patients.
Volume 15 Suppl 1 (8 November 2013)
Liverpool, UK. 10-12 November 2013
Aims & scope
Breast Cancer Research is an international, peer-reviewed online journal, publishing original research, reviews, editorials and reports. Open access research articles of exceptional interest are published in all areas of biology and medicine relevant to breast cancer, including normal mammary gland biology, with special emphasis on the genetic, biochemical, and cellular basis of breast cancer. In addition to basic research, the journal publishes preclinical, translational and clinical studies with a biological basis, including Phase I and Phase II trials.
All reviews, commentaries and reports published in Breast Cancer Research become free to access 6 months after publication. See below for the latest free review.
Jagdeep K Singh, Bruno M Simões, Sacha J Howell, Gillian Farnie, Robert B ClarkeBreast Cancer Research 2013, 15:210
(30 August 2013)
- 07 April 2014
- Buparlisib shows promise in metastatic breast cancer
- 02 April 2014
- Pre-cancerous breast cancer cells treated with a vitamin A derivative revert into non-cancerous cells
- 26 March 2014
- Minimally invasive treatment may slow disease progression of metastatic breast cancer in liver while maintaining quality of life