Editor-in-Chief

  • Lewis Chodosh, University of Pennsylvania

Articles

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  • The Angelina Jolie effect on breast cancer referrals

    The publicity surrounding actress Angelina Jolie’s decision to undergo genetic testing for the BRCA1 gene and subsequently a risk reducing mastectomy has resulted in an increase of referrals to clinics in the UK.

    Breast Cancer Research 2014, 16:442
  • Mammographic images can distinguish BRCA1/2 status

    Digitized mammographic images contain computer-extractable information of the parenchymal pattern not captured during routine radiologic interpretation, which have the potential to distinguish between BRCA1/2 mutation carriers and non-carriers.

    Breast Cancer Research 2014, 16:424
  • Physical activity and cellular aging in breast cancer survivors

    A self-reported lack of physical activity was associated with shortened telomere length in early stage breast cancer survivors, suggesting a mechanism by which exercise can reduce cellular aging.

    Breast Cancer Research 2014, 16:413
  • Dual HER2 targeted treatments: preclinical and clinical data

    Chang, Perez, and colleagues, review recent data on different combinations of anti-human epidermal growth factor receptor (HER2) treatments, as part of the ‘recent advances in breast cancer treatment’ special series.

    Breast Cancer Research 2014, 16:419
  • Exploiting the reversibility of epigenetic mutations

    Rots and colleagues describe aberrant DNA methylation and histone modifications as two important classes of epigenetic mutations in breast cancer and review the preclinical and clinical epigenetic-based therapies currently being explored.

    Breast Cancer Research 2014, 16:412
  • Novel biomarker panel for breast cancer

    Five serum proteins can distinguish between serum from women with breast cancer and healthy control subjects with high sensitivity and specificity and can significantly predict recurrence-free survival in women with estrogen receptor negative tumors.

    Breast Cancer Research 2014, 16:R63

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Open Access Research

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Aims & scope

Breast Cancer Research is an international, peer-reviewed online journal, publishing original research, reviews, editorials and reports. Open access research articles of exceptional interest are published in all areas of biology and medicine relevant to breast cancer, including normal mammary gland biology, with special emphasis on the genetic, biochemical, and cellular basis of breast cancer. In addition to basic research, the journal publishes preclinical, translational and clinical studies with a biological basis, including Phase I and Phase II trials.

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Breast Cancer Research Volume 16 Issue 4

The complete issue of Breast Cancer Research Volume 16 Issue 4 is now available.

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Immune approaches to the treatment of breast cancer, around the corner?

Carmen Criscitiello, Angela Esposito, Lucia Gelao, Luca Fumagalli, Marzia Locatelli, Ida Minchella, Laura Adamoli, Aron Goldhirsch, Giuseppe Curigliano

Breast Cancer Research 2014, 16:204 (25 February 2014)
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ISSN: 1465-5411