• Lewis Chodosh, University of Pennsylvania


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  • Computer-aided discovery of new breast cancer therapeutics

    A combination of virtual screening and biochemical assays identified new small-molecule estrogen receptor inhibitors with the potential for use in novel endocrine-based therapies.

    Breast Cancer Research 2015, 17:27
  • Assessing insulin analogues for breast cancer risk

    A human-relevant mouse model is used to determine the carcinogenic potential of diabetes drugs, finding a link between insulin-like molecules with high mitogenic activity and increased risk of breast cancer development.  

    Breast Cancer Research 2015, 17:14
  • Better prediction of cancer survival

    E2F4 transcription factor activity in tumors can be used to predict the survival outcomes of breast cancer patients, providing a prognostic molecular signature with potential for use across many clinical contexts.

    Breast Cancer Research 2014, 16:486
  • Addressing key gaps in risk and prevention

    Howell and colleagues from the BCC risk-and-prevention panel report on how adding new, but available, information to current risk models could ultimately better predict a woman’s individual breast cancer risk.

    Breast Cancer Research 2014, 16:446



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Latest supplements

Volume 16 Suppl 1 (3 November 2014)

British Society of Breast Radiology Annual Scientific Meeting 2014

Meeting abstracts
Brighton, UK. 10-11 November 2014

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Lobular breast cancer: read the review series
Editors thank those reviewing manuscripts in 2014

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Aims & scope

Breast Cancer Research is an international, peer-reviewed online journal, publishing original research, reviews, editorials and reports. Open access research articles of exceptional interest are published in all areas of biology and medicine relevant to breast cancer, including normal mammary gland biology, with special emphasis on the genetic, biochemical, and cellular basis of breast cancer. In addition to basic research, the journal publishes preclinical, translational and clinical studies with a biological basis, including Phase I and Phase II trials.

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  • Lobular Breast Cancer
    Edited by: Prof Ulrich Lehmann
    Published: 29 January 2015
    Last updated: 8 February 2015

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Featured review


Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer

Reuben S Harris

Breast Cancer Research 2014, 17:8 (21 January 2015)
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ISSN: 1465-5411