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		Research article Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development Martin A Rivas, Leandro Venturutti, Yi-Wen Huang, Roxana Schillaci, Tim HUI-MING Huang, Patricia V Elizalde Breast Cancer Research 2012, 14:R77 (14 May 2012) Abstract \| Provisional PDF
		Research article Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study Rebecca E Ritte, Annekatrin Lukanova, Franco Berrino, Laure Dossus, Anne Tjonneland, Anja Olsen, Thure F Overvad, Kim Overvad, Francoise Clavel-Chapelon, Agnes Fournier, Guy Fagherazzi, Sabine Rohrmann, Birgit Teucher, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sabina Sieri, Salvatore Panico, Rosario Tumino, Paolo Vineis, Jose Ramon Quiros, Genevieve Buckland, Maria-Jose Sanchez, Pilar Amiano, Maria-Dolores Chirlaque, Eva Ardanaz, Malin Sund et al. Breast Cancer Research 2012, 14:R76 (14 May 2012) Abstract \| Provisional PDF
		Research article Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer Luigi Strizzi, Katharine M Hardy, Naira V Margaryan, David W Hillman, Elisabeth A Seftor, Beiyun Chen, Xochiquetzal J Geiger, E AUBREY Thompson, Wilma L Lingle, Cathy A Andorfer, Edith A Perez, Mary JC Hendrix Breast Cancer Research 2012, 14:R75 (11 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The embryonic morphogen Nodal is associated with advanced stage invasive human breast cancer, and may have a role as both a prognostic biomarker and a therapeutic target.
		Viewpoint Estrogen-related receptor alpha: an orphan finds a family Aleksandra M Ochnik, Douglas Yee Breast Cancer Research 2012, 14:309 (10 May 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Crk adaptor proteins act as key signaling integrators for breast tumorigenesis Kelly E Fathers, Emily S Bell, Charles V Rajadurai, Sean Cory, Hong Zhao, Anna Mourskaia, Dongmei Zuo, Jason Madore, Anie Monast, Anne-Marie Mes-Masson, Andree-Anne Grosset, Louis Gaboury, Michael Hallett, Peter Siegel, Morag Park Breast Cancer Research 2012, 14:R74 (8 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer Xiao Wu, Zhengmao Zhu, Weidong Li, Xiaoying Fu, Dan Su, Liya Fu, Zhiqian Zhang, Ang Luo, Xiaodong Sun, Li Fu, Jin-Tang Dong Breast Cancer Research 2012, 14:R73 (8 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article CENP-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer Susan L McGovern, Yuan Qi, Lajos Pusztai, William F Symmans, Thomas A Buchholz Breast Cancer Research 2012, 14:R72 (4 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The essential centromere protein, CENP-A, is a strong prognostic marker for distant relapse in estrogen-receptor positive breast cancer not treated with systemic therapy, and may contribute to disease progression.
		Research article Biomarkers Characterization of Circulating Tumour Cells in Breast Cancer Patients Rosa M Nadal, Ana Fernandez, Pedro Sanchez-Rovira, Marta Salido, Maria Rodriguez, Jose L Garcia-Puche, Marta Macia, Josep M Coromines, Miguel Delgado-Rodriguez, Lucas Gonzalez, Joan Albanell, Monica Fernandez, Francesc Sole, Jose A Lorente, M. Jose Serrano Breast Cancer Research 2012, 14:R71 (3 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Prognostic and predictive value of TP53 mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane based adjuvant therapy: results from the BIG 02-98 phase III trial Lynnette Fernandez-Cuesta, Catherine Oakman, Priscila Falagan-Lotsch, Ke-seay Smoth, Emmanuel Quinaux, Marc Buyse, M STELLA Dolci, Evandro De Azambuja, Pierre Hainaut, Patrizia Dell'Orto, Denis Larsimont, Prudence A Francis, John Crown, Martine Piccart-Gebhart, Giuseppe Viale, Angelo Di Leo, Magali Olivier Breast Cancer Research 2012, 14:R70 (2 May 2012) Abstract \| Provisional PDF \| PubMed
		Viewpoint Adjuvant treatment of HER2-positive breast cancer: winning efforts continue to improve HER2-positive patient outcome long-term Rachel C Jankowitz, Adam M Brufsky Breast Cancer Research 2012, 14:308 (30 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, but not BRCA1 familial breast cancers Max Yan, Huiling Xu, Nic Waddell, Kristy Shield, Izhak Haviv, kConFab Authors, Michael J McKay, Stephen B Fox Breast Cancer Research 2012, 14:R69 (26 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article CIP2A is a target of bortezomib in human triple negative breast cancer cells Ling-Ming Tseng, Chun-Yu Liu, Kung-Chi Chang, Pei-Yi Chu, Chung-Wai Shiau, Kuen-Feng Chen Breast Cancer Research 2012, 14:R68 (26 April 2012) Abstract \| Provisional PDF \| PubMed
		Viewpoint PTHrP and breast cancer: more than hypercalcemia and bone metastases Kata Boras-Granic, John J Wysolmerski Breast Cancer Research 2012, 14:307 (25 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan Krissa Gibby, Weon-Kyoo You, Kuniko Kadoya, Hildur Helgadottir, Lawrence JT Young, Lesley G Ellies, Yunchao Chang, Robert D Cardiff, William B Stallcup Breast Cancer Research 2012, 14:R67 (24 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer Rachel L Dusek, Jamie L Bascom, Hannes Vogel, Sylvain Baron, Alexander D Borowsky, Mina J Bissell, Laura D Attardi Breast Cancer Research 2012, 14:R65 (20 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The protein Perp, associated with desmosomes - the glue that sticks cells together - is involved in suppressing breast cancer and provides a potential new target for future treatment.
		Letter Frequency of the CHEK2 1100delC mutation among women with early-onset and bilateral breast cancer Dapeng Ding, Ying Zhang, Xiaofeng He, Wei Meng, Wenli Ma, Wenling Zheng Breast Cancer Research 2012, 14:401 (20 April 2012) Abstract \| Full text \| PDF \| PubMed
		Review In vivo proton magnetic resonance spectroscopy of breast cancer: a review of the literature Jonathan KP Begley, Thomas W Redpath, Patrick J Bolan, Fiona J Gilbert Breast Cancer Research 2012, 14:207 (19 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers Xiaohong R Yang, Jonine D Figueroa, Roni T Falk, Hong Zhang, Ruth M Pfeiffer, Stephen M Hewitt, Jolanta Lissowska, Beata Peplonska, Louise Brinton, Montserrat Garcia-Closas, Mark E Sherman Breast Cancer Research 2012, 14:R64 (18 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers Ana-Teresa Maia, Antonis C Antoniou, Martin O'Reilly, Shamith Samarajiwa, Mark Dunning, Christiana Kartsonaki, Suet-Feung Chin, Christina N Curtis, Lesley McGuffog, Susan M Domchek, EMBRACE, Douglas F Easton, Susan Peock, Debra Frost, D Evans, Ros Eeles, Louise Izatt, Julian Adlard, Diana Eccles, GEMO Study Collaborators, Olga M Sinilnikova, Sylvie Mazoyer, Dominique Stoppa-Lyonnet, Marion Gauthier-Villars, Laurence Faivre, Laurence Venat-Bouvet, Capucine Delnatte, Heli Nevanlinna, Fergus J Couch, Andrew K Godwin, Maria Caligo, SWE-BRCA, Rosa B Barkardottir, kConFab Investigators, Xiaoqing Chen et al. Breast Cancer Research 2012, 14:R63 (18 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer Qing Cheng, Jeffrey T Chang, Joseph Geradts, Leonard M Neckers, Timothy Haystead, Neil L Spector, H Kim Lyerly Breast Cancer Research 2012, 14:R62 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article In vivo breast cancer characterization imaging using two monoclonal antibodies activatably labeled with near infrared fluorophores Kohei Sano, Makoto Mitsunaga, Takahito Nakajima, Peter L Choyke, Hisataka Kobayashi Breast Cancer Research 2012, 14:R61 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients Daphne SC Lee, Sook-Yee Yoon, Lai Looi, Peter Kang, In Kang, Kavitta Sivanandan, Hany Ariffin, Meow Thong, Kin Chin, Nur Mohd Taib, Cheng-Har Yip, Soo-Hwang Teo Breast Cancer Research 2012, 14:R66 (16 April 2012) Abstract \| Full text \| PDF
		Research article RAC1 GTPase plays an important role in γ-irradiation induced G₂/M checkpoint activation Ying Yan, Patrick M Greer, Phu T Cao, Ryan H Kolb, Kenneth H Cowan Breast Cancer Research 2012, 14:R60 (11 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Characterizing mammographic images by using generic texture features Lothar Häberle, Florian Wagner, Peter A Fasching, Sebastian M Jud, Katharina Heusinger, Christian R Loehberg, Alexander Hein, Christian M Bayer, Carolin C Hack, Michael P Lux, Katja Binder, Matthias Elter, Christian Münzenmayer, Rüdiger Schulz-Wendtland, Martina Meier-Meitinger, Boris R Adamietz, Michael Uder, Matthias W Beckmann, Thomas Wittenberg Breast Cancer Research 2012, 14:R59 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Viewpoint BRCA1 as tumor suppressor: lord without its RING? Andrew EH Elia, Stephen J Elledge Breast Cancer Research 2012, 14:306 (10 April 2012) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development Martin A Rivas, Leandro Venturutti, Yi-Wen Huang, Roxana Schillaci, Tim HUI-MING Huang, Patricia V Elizalde Breast Cancer Research 2012, 14:R77 (14 May 2012) Abstract \| Provisional PDF
		Research article Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study Rebecca E Ritte, Annekatrin Lukanova, Franco Berrino, Laure Dossus, Anne Tjonneland, Anja Olsen, Thure F Overvad, Kim Overvad, Francoise Clavel-Chapelon, Agnes Fournier, Guy Fagherazzi, Sabine Rohrmann, Birgit Teucher, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sabina Sieri, Salvatore Panico, Rosario Tumino, Paolo Vineis, Jose Ramon Quiros, Genevieve Buckland, Maria-Jose Sanchez, Pilar Amiano, Maria-Dolores Chirlaque, Eva Ardanaz, Malin Sund et al. Breast Cancer Research 2012, 14:R76 (14 May 2012) Abstract \| Provisional PDF
		Research article Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer Luigi Strizzi, Katharine M Hardy, Naira V Margaryan, David W Hillman, Elisabeth A Seftor, Beiyun Chen, Xochiquetzal J Geiger, E AUBREY Thompson, Wilma L Lingle, Cathy A Andorfer, Edith A Perez, Mary JC Hendrix Breast Cancer Research 2012, 14:R75 (11 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The embryonic morphogen Nodal is associated with advanced stage invasive human breast cancer, and may have a role as both a prognostic biomarker and a therapeutic target.
		Viewpoint Estrogen-related receptor alpha: an orphan finds a family Aleksandra M Ochnik, Douglas Yee Breast Cancer Research 2012, 14:309 (10 May 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Crk adaptor proteins act as key signaling integrators for breast tumorigenesis Kelly E Fathers, Emily S Bell, Charles V Rajadurai, Sean Cory, Hong Zhao, Anna Mourskaia, Dongmei Zuo, Jason Madore, Anie Monast, Anne-Marie Mes-Masson, Andree-Anne Grosset, Louis Gaboury, Michael Hallett, Peter Siegel, Morag Park Breast Cancer Research 2012, 14:R74 (8 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer Xiao Wu, Zhengmao Zhu, Weidong Li, Xiaoying Fu, Dan Su, Liya Fu, Zhiqian Zhang, Ang Luo, Xiaodong Sun, Li Fu, Jin-Tang Dong Breast Cancer Research 2012, 14:R73 (8 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article CENP-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer Susan L McGovern, Yuan Qi, Lajos Pusztai, William F Symmans, Thomas A Buchholz Breast Cancer Research 2012, 14:R72 (4 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The essential centromere protein, CENP-A, is a strong prognostic marker for distant relapse in estrogen-receptor positive breast cancer not treated with systemic therapy, and may contribute to disease progression.
		Research article Biomarkers Characterization of Circulating Tumour Cells in Breast Cancer Patients Rosa M Nadal, Ana Fernandez, Pedro Sanchez-Rovira, Marta Salido, Maria Rodriguez, Jose L Garcia-Puche, Marta Macia, Josep M Coromines, Miguel Delgado-Rodriguez, Lucas Gonzalez, Joan Albanell, Monica Fernandez, Francesc Sole, Jose A Lorente, M. Jose Serrano Breast Cancer Research 2012, 14:R71 (3 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Prognostic and predictive value of TP53 mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane based adjuvant therapy: results from the BIG 02-98 phase III trial Lynnette Fernandez-Cuesta, Catherine Oakman, Priscila Falagan-Lotsch, Ke-seay Smoth, Emmanuel Quinaux, Marc Buyse, M STELLA Dolci, Evandro De Azambuja, Pierre Hainaut, Patrizia Dell'Orto, Denis Larsimont, Prudence A Francis, John Crown, Martine Piccart-Gebhart, Giuseppe Viale, Angelo Di Leo, Magali Olivier Breast Cancer Research 2012, 14:R70 (2 May 2012) Abstract \| Provisional PDF \| PubMed
		Viewpoint Adjuvant treatment of HER2-positive breast cancer: winning efforts continue to improve HER2-positive patient outcome long-term Rachel C Jankowitz, Adam M Brufsky Breast Cancer Research 2012, 14:308 (30 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, but not BRCA1 familial breast cancers Max Yan, Huiling Xu, Nic Waddell, Kristy Shield, Izhak Haviv, kConFab Authors, Michael J McKay, Stephen B Fox Breast Cancer Research 2012, 14:R69 (26 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article CIP2A is a target of bortezomib in human triple negative breast cancer cells Ling-Ming Tseng, Chun-Yu Liu, Kung-Chi Chang, Pei-Yi Chu, Chung-Wai Shiau, Kuen-Feng Chen Breast Cancer Research 2012, 14:R68 (26 April 2012) Abstract \| Provisional PDF \| PubMed
		Viewpoint PTHrP and breast cancer: more than hypercalcemia and bone metastases Kata Boras-Granic, John J Wysolmerski Breast Cancer Research 2012, 14:307 (25 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan Krissa Gibby, Weon-Kyoo You, Kuniko Kadoya, Hildur Helgadottir, Lawrence JT Young, Lesley G Ellies, Yunchao Chang, Robert D Cardiff, William B Stallcup Breast Cancer Research 2012, 14:R67 (24 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer Rachel L Dusek, Jamie L Bascom, Hannes Vogel, Sylvain Baron, Alexander D Borowsky, Mina J Bissell, Laura D Attardi Breast Cancer Research 2012, 14:R65 (20 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The protein Perp, associated with desmosomes - the glue that sticks cells together - is involved in suppressing breast cancer and provides a potential new target for future treatment.
		Letter Frequency of the CHEK2 1100delC mutation among women with early-onset and bilateral breast cancer Dapeng Ding, Ying Zhang, Xiaofeng He, Wei Meng, Wenli Ma, Wenling Zheng Breast Cancer Research 2012, 14:401 (20 April 2012) Abstract \| Full text \| PDF \| PubMed
		Review In vivo proton magnetic resonance spectroscopy of breast cancer: a review of the literature Jonathan KP Begley, Thomas W Redpath, Patrick J Bolan, Fiona J Gilbert Breast Cancer Research 2012, 14:207 (19 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers Xiaohong R Yang, Jonine D Figueroa, Roni T Falk, Hong Zhang, Ruth M Pfeiffer, Stephen M Hewitt, Jolanta Lissowska, Beata Peplonska, Louise Brinton, Montserrat Garcia-Closas, Mark E Sherman Breast Cancer Research 2012, 14:R64 (18 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers Ana-Teresa Maia, Antonis C Antoniou, Martin O'Reilly, Shamith Samarajiwa, Mark Dunning, Christiana Kartsonaki, Suet-Feung Chin, Christina N Curtis, Lesley McGuffog, Susan M Domchek, EMBRACE, Douglas F Easton, Susan Peock, Debra Frost, D Evans, Ros Eeles, Louise Izatt, Julian Adlard, Diana Eccles, GEMO Study Collaborators, Olga M Sinilnikova, Sylvie Mazoyer, Dominique Stoppa-Lyonnet, Marion Gauthier-Villars, Laurence Faivre, Laurence Venat-Bouvet, Capucine Delnatte, Heli Nevanlinna, Fergus J Couch, Andrew K Godwin, Maria Caligo, SWE-BRCA, Rosa B Barkardottir, kConFab Investigators, Xiaoqing Chen et al. Breast Cancer Research 2012, 14:R63 (18 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer Qing Cheng, Jeffrey T Chang, Joseph Geradts, Leonard M Neckers, Timothy Haystead, Neil L Spector, H Kim Lyerly Breast Cancer Research 2012, 14:R62 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article In vivo breast cancer characterization imaging using two monoclonal antibodies activatably labeled with near infrared fluorophores Kohei Sano, Makoto Mitsunaga, Takahito Nakajima, Peter L Choyke, Hisataka Kobayashi Breast Cancer Research 2012, 14:R61 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients Daphne SC Lee, Sook-Yee Yoon, Lai Looi, Peter Kang, In Kang, Kavitta Sivanandan, Hany Ariffin, Meow Thong, Kin Chin, Nur Mohd Taib, Cheng-Har Yip, Soo-Hwang Teo Breast Cancer Research 2012, 14:R66 (16 April 2012) Abstract \| Full text \| PDF
		Research article RAC1 GTPase plays an important role in γ-irradiation induced G₂/M checkpoint activation Ying Yan, Patrick M Greer, Phu T Cao, Ryan H Kolb, Kenneth H Cowan Breast Cancer Research 2012, 14:R60 (11 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Characterizing mammographic images by using generic texture features Lothar Häberle, Florian Wagner, Peter A Fasching, Sebastian M Jud, Katharina Heusinger, Christian R Loehberg, Alexander Hein, Christian M Bayer, Carolin C Hack, Michael P Lux, Katja Binder, Matthias Elter, Christian Münzenmayer, Rüdiger Schulz-Wendtland, Martina Meier-Meitinger, Boris R Adamietz, Michael Uder, Matthias W Beckmann, Thomas Wittenberg Breast Cancer Research 2012, 14:R59 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Viewpoint BRCA1 as tumor suppressor: lord without its RING? Andrew EH Elia, Stephen J Elledge Breast Cancer Research 2012, 14:306 (10 April 2012) Abstract \| Full text \| PDF \| PubMed