Commentary Fatal attraction: why breast cancer cells home to boneLorenz C Hofbauer1 1Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technical University, D-01307 Dresden, Germany 2Department of Medicine, Philipps-University, D-35033 Marburg, Germany
Breast Cancer Research 2008, 10:101doi:10.1186/bcr1848
AbstractOsteolytic metastases due to breast cancer are serious events. The interactions between breast cancer cells with the microenvironment of bone have been thought to provide an ideal milieu for cancer cells. Recent data now indicate that migration of breast cancer cells into bone and their subsequent growth into metastases depends upon the interaction of the receptor activator of NF-κB ligand (RANKL) with its receptor RANK. |
|
 |  | Log on / register BioMed Central home | Journals A-Z | Feedback | Support |
home | issues | articles | reports | supplements | weblinks | conferences | search | information | subscribe | my details |
on Google Scholar
author email
corresponding author email|
| Published by |  |
| © 1999-2008 BioMed Central Ltd unless otherwise stated < info@breast-cancer-research.com > Terms and conditions |