Breast Cancer Research

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Prognostic ability of a panel of immunohistochemistry markers – retailoring of an 'old solution'

Donal J Brennan and William M Gallagher*

Breast Cancer Research 2008, 10:102 doi:10.1186/bcr1854

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Protein expression based multimarker analysis of breast cancer samples

Angela P Presson, Nam K Yoon, Lora Bagryanova, Vei Mah, Mohammad Alavi, Erin L Maresh, Ayyappan K Rajasekaran, Lee Goodglick, David Chia, Steve Horvath BMC Cancer 2011, 11:230 (8 June 2011)

Abstract | Full text | PDF | PubMed

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Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

Elton Rexhepaj, Donal J Brennan, Peter Holloway, Elaine W Kay, Amanda H McCann, Goran Landberg, Michael J Duffy, Karin Jirstrom, William M Gallagher Breast Cancer Research 2008, 10:R89 (23 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

The automated quantification of estrogen and progesterone receptors in 743 primary breast tumours using a novel unsupervised image analysis algorithm provides a useful tool to quantify biomarkers on tissue specimens.

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