Research article
Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients
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* Corresponding author: Giske Ursin gursin@usc.edu
1 Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90089-9175, USA
2 Institute for Health Promotion and Disease Prevention Research, Keck School of Medicine, University of Southern California, Alhambra, CA 91803, USA
3 Children's Oncology Group, Arcadia, CA 91066, USA
4 City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, CA 91010, USA
5 Department of Nutrition, University of Oslo, Norway
Breast Cancer Research 2008, 10:R19 doi:10.1186/bcr1865
Published: 19 February 2008Additional files
Additional file 1:
Word file containing the detailed sequencing procedures and the classification approach integrating sequence conservation and the GMS.
Format: DOC Size: 36KB Download file
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Additional file 2:
Word file containing a table listing the protein sequences used for cross-species comparison of BRCA1 and BRCA2.
Format: DOC Size: 38KB Download file
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Additional file 3:
Word file containing a table listing all of the BRCA1/BRCA2 variants identified in this study along with our classification of each variant in comparison with the classification according to the BIC database.
Format: DOC Size: 711KB Download file
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