Figure 2.

Anti-HER1–HER4 FISH in breast cancer tissue of one patient (dual probes). HER1: red cen 7, green loc 7p11 (diploid); HER2: red cen 17, green loc 17q12 (amplified); HER3: green cen 12, red loc 12q13 (moderately amplified); HER4: green cen 2, red loc 2q33 (diploid); 4',6-diamidino-2-phenylindole core staining blue. Cen, centromere; loc, gene locus.