Table 5 |
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|
Multivariate analysis of relapse-free survival in the test set for all eight tissue microarray biomarkers |
||
| Biomarker |
HR (95% CI) |
P |
|
|
||
| ER |
0.87 (0.55–1.38) |
0.5 |
| PR |
0.58 (0.39–0.86) |
0.006 |
| HER2 |
0.93 (0.61–1.42) |
0.7 |
| EGFR |
1.20 (0.63–2.29) |
0.6 |
| Ki-67 |
1.99 (1.32–3.00) |
0.001 |
| p53 |
0.88 (0.58–1.35) |
0.6 |
| CA IX |
1.67 (1.06–2.64) |
0.03 |
| CK5/6 |
0.81 (0.43–1.54) |
0.5 |
|
|
||
|
ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; EGFR, human epidermal growth factor receptor 1; CA IX, carbonic anhydrase IX; CK5/6, cytokeratin 5/6; HR, hazard ratio for positive expression status for that marker; CI, confidence interval. |
||
|
Crabb et al. Breast Cancer Research 2008 10:R6 doi:10.1186/bcr1847 |
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