Figure 1.

Detection of activator protein 2 alpha (AP-2α), Yin Yang 1 (YY1), and ERBB2 by immunohistochemistry in breast tumors. (a) Case with low immunoreactivity for AP-2α. (b) Tumor sample expressing high level of AP-2α protein in more than 80% of the nuclei.(c) Tumor with low immunoreactivity for YY1. (d) Case expressing high level of YY1 protein in more than 80% of the nuclei. (e) Case with no ERBB2 membrane staining, scored as IHC 0. (f) Tumor with partial weak membrane staining, scored as IHC 1+. (g) Case with ERBB2 score of 2+. (h) Tumor with thick circumferential ERBB2 membrane staining, scored as IHC 3+.