Table 3

Associations between ERBB2 and AP-2α and/or YY1 levels determined by immunohistochemistry


ERBB2 expression (percentage)

n
 0/1+
 2+
 3+
 P value
AP-2α expression






0.003
     Low
 32
 19
 (59)
 5
 (16)
 8
 (25)
     High
 23
 4
 (17)
 12
 (52)
 7
 (31)









YY1 expression






0.318
     Low
 30
 15
 (50)
 7
 (23)
 8
 (27)
     High
 25
 8
 (32)
 10
 (40)
 7
 (28)









Combination






0.016
     AP-2α lo/YY1 lo
 26
 14
 (54)
 4
 (15)
 8
 (31)
     AP-2α lo/YY1 hi or AP-2α hi/YY1 lo
 10
 6
 (60)
 4
 (40)
 0
 (0)
     AP-2α hi/YY1 hi
 19
 3
 (16)
 9
 (47)
 7
 (37)

AP-2α, activator protein 2 alpha; hi, high expression; lo, low expression; YY1, Yin Yang 1.

Allouche et al. Breast Cancer Research 2008 10:R9   doi:10.1186/bcr1851