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Volume 10 Issue 2
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Comment |
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Breast Cancer Research – the first ten years
Frances Mulvany, Bruce AJ Ponder Breast Cancer Research 2008, 10:103 (10 March 2008)
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Breast cancer surface receptors predict risk for developing brain metastasis and subsequent prognosis
Jai Grewal, Santosh Kesari Breast Cancer Research 2008, 10:104 (14 March 2008)
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Cancer stem cell heterogeneity in hereditary breast cancer
Max S Wicha Breast Cancer Research 2008, 10:105 (16 April 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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NHERF1: molecular brake on the PI3K pathway in breast cancer
Maria-Magdalena Georgescu Breast Cancer Research 2008, 10:106 (18 April 2008)
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Breast cancer metastasis: a microRNA story
Massimo Negrini, George Calin Breast Cancer Research 2008, 10:303 (26 March 2008)
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Review |
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Tissue factor, angiogenesis and tumour progression
Joanne E Bluff, Nicola J Brown, Malcolm WR Reed, Carolyn A Staton Breast Cancer Research 2008, 10:204 (17 March 2008)
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Inflammation and breast cancer. Metalloproteinases as common effectors of inflammation and extracellular matrix breakdown in breast cancer
Carlo V Hojilla, Geoffrey A Wood, Rama Khokha Breast Cancer Research 2008, 10:205 (31 March 2008)
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Cancer and fertility preservation: fertility preservation in breast cancer patients
Theodoros Maltaris, Michael Weigel, Andreas Mueller, Marcus Schmidt, Rudolf Seufert, Franz Fischl, Heinz Koelbl, Ralf Dittrich Breast Cancer Research 2008, 10:206 (29 April 2008)
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Research |
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Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer
Aparna Mitra, Rebecca A Fillmore, Brandon J Metge, Mathur Rajesh, Yaguang Xi, Judy King, Jingfang Ju, Lewis Pannell, Lalita A Shevde, Rajeev S Samant Breast Cancer Research 2008, 10:R22 (7 March 2008)
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Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG)
Alexander Wall, Thorsten Persigehl, Peter Hauff, Kai Licha, Michael Schirner, Silke Müller, Angelika von Wallbrunn, Lars Matuszewski, Walter Heindel, Christoph Bremer Breast Cancer Research 2008, 10:R23 (10 March 2008)
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Editor’s summary
Perfusion-type cyanine dyes allow for the assessment of angiogenesis in breast cancer tumors using imaging technology, and therefore may help to facilitate the characterization of solid tumors.
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Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials
Marianne Kyndi, Flemming B Sørensen, Helle Knudsen, Jan Alsner, Marie Overgaard, Hanne M Nielsen, Jens Overgaard Breast Cancer Research 2008, 10:R24 (20 March 2008)
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Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
Christine M Fillmore, Charlotte Kuperwasser Breast Cancer Research 2008, 10:R25 (26 March 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Evaluation of the current knowledge limitations in breast cancer research: a gap analysis
Alastair Thompson, Keith Brennan, Angela Cox, Julia Gee, Diana Harcourt, Adrian Harris, Michelle Harvie, Ingunn Holen, Anthony Howell, Robert Nicholson, Michael Steel, Charles Streuli, Breast Cancer Campaign Gap Analysis Meeting (2 November 2006, London, UK) Breast Cancer Research 2008, 10:R26 (27 March 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A comprehensive review of the seven main research areas by 56 experts has identified the key gaps and priorities for the greatest potential impact on breast cancer patients.
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PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer
Cornelia Liedtke, Luca Cardone, Attila Tordai, Kai Yan, Henry L Gomez, Luis Figureoa, Rebekah E Hubbard, Vicente Valero, Eduardo A Souchon, W Fraser Symmans, Gabriel N Hortobagyi, Alberto Bardelli, Lajos Pusztai Breast Cancer Research 2008, 10:R27 (27 March 2008)
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The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome
Alison J Butt, C Marcelo Sergio, Claire K Inman, Luke R Anderson, Catriona M McNeil, Amanda J Russell, Marco Nousch, Thomas Preiss, Andrew V Biankin, Robert L Sutherland, Elizabeth A Musgrove Breast Cancer Research 2008, 10:R28 (29 March 2008)
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Editor’s summary
Transcript profiling identified an estrogen-responsive target for the mammary oncogene c-Myc, HSPC111, which is overexpressed in breast cancer cells and is associated with adverse patient outcome.
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Involvement of a specificity proteins-binding element in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene
Jennifer K Hockings, Stephanie C Degner, Sherif S Morgan, Michael Q Kemp, Donato F Romagnolo Breast Cancer Research 2008, 10:R29 (31 March 2008)
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Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast
Gunter von Minckwitz, Hans-Peter Sinn, Günter Raab, Sibylle Loibl, Jens-Uwe Blohmer, Holger Eidtmann, Jörn Hilfrich, Elisabeth Merkle, Christian Jackisch, Serban D Costa, Angelika Caputo, Manfred Kaufmann, the German Breast Group (GBG) Breast Cancer Research 2008, 10:R30 (1 April 2008)
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Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk
Sascha Abbas, Alexandra Nieters, Jakob Linseisen, Tracy Slanger, Silke Kropp, Elke Mutschelknauss, Dieter Flesch-Janys, Jenny Chang-Claude Breast Cancer Research 2008, 10:R31 (17 April 2008)
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Editor’s summary
A large case-control study found no association between vitamin D receptor polymorphisms and overall breast cancer risk, but the TaqI polymorphism was associated with a significantly increased risk of estrogen-receptor positive breast cancer.
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Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study
Heather Ward, Gaelle Chapelais, Gunter GC Kuhnle, Robert Luben, Kay-Tee Khaw, Sheila Bingham Breast Cancer Research 2008, 10:R32 (17 April 2008)
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Editor’s summary
The majority of phytoestrogen biomarkers were not associated with breast cancer risk in a study of 237 cases, but limited evidence of an association between urinary equol and ER-positive breast cancer warrants further investigation.
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NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models
Michael Jensen, Joseph Schoepfer, Thomas Radimerski, Andrew Massey, Chantale T Guy, Josef Brueggen, Cornelia Quadt, Alan Buckler, Robert Cozens, Martin J Drysdale, Carlos Garcia-Echeverria, Patrick Chène Breast Cancer Research 2008, 10:R33 (22 April 2008)
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Gene expression profiling in primary breast cancer distinguishes patients developing local recurrence after breast-conservation surgery, with or without postoperative radiotherapy
Emma Niméus-Malmström, Morten Krogh, Per Malmström, Carina Strand, Irma Fredriksson, Per Karlsson, Bo Nordenskjöld, Olle Stål, Görel Östberg, Carsten Peterson, Mårten Fernö Breast Cancer Research 2008, 10:R34 (22 April 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer
Yasmine Nadler, Robert L Camp, Jennifer M Giltnane, Christopher Moeder, David L Rimm, Harriet M Kluger, Yuval Kluger Breast Cancer Research 2008, 10:R35 (23 April 2008)
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TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells
Jillian Howlin, Jeanette Rosenkvist, Tommy Andersson Breast Cancer Research 2008, 10:R36 (24 April 2008)
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Evaluation of biological pathways involved in chemotherapy response in breast cancer
Attila Tordai, Jing Wang, Fabrice Andre, Cornelia Liedtke, Kai Yan, Christos Sotiriou, Gabriel N Hortobagyi, W Fraser Symmans, Lajos Pusztai Breast Cancer Research 2008, 10:R37 (29 April 2008)
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Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health–AARP Diet and Health Study
Gretchen L Gierach, James V Lacey, Arthur Schatzkin, Michael F Leitzmann, Douglas Richesson, Albert R Hollenbeck, Louise A Brinton Breast Cancer Research 2008, 10:R38 (30 April 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A study of over 127,000 women found that NSAIDS do not influence total breast cancer risk, however daily aspirin use appeared to offer some protection against estrogen receptor-positive breast cancer.
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Correspondence |
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Incorporating tumor immunohistochemical markers in BRCA1 and BRCA2 carrier prediction
Yu Tai, Sining Chen, Giovanni Parmigiani, Alison P Klein Breast Cancer Research 2008, 10:401 (20 March 2008)
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