Table 2

Antiproliferative effect of NVP-AUY922 against primary breast cancer

Cell line
IC50
IC70



nM

MAXF 1162
304
505
MAXF 1322
29
48
MAXF 1384
209
477
MAXF 401
78
295
MAXF 574
>10,000
>10,000
MAXF 583
333
569

The concentrations of NVP-AUY922 that inhibit colony formation by 50% (IC50) or 70% (IC70) were determined (Oncotest GmbH, Freiburg, Germany) [24].

Jensen et al. Breast Cancer Research 2008 10:R33   doi:10.1186/bcr1996