Figure 2.

Gene set enrichment results for estrogen receptor-negative breast tumors. Running enrichment scores (RESs) and the location of each probe set within the complete rank-ordered gene list for each gene set. The dotted line on the left indicates the position of the maximum RES, and the dotted line on the right indicates the zero position of the ranking metric score. (a) Proliferation set (probe set n = 74). (b) Genomic grade index (probe set n = 242). (c) E2F3 pathway (probe set n = 173). Heat maps corresponding to these plots are provided in Supplementary Figure 1. pCR, pathologic complete response; RD, residual disease.