Table 1

Distribution of select risk factors across categories of aspirin use among 126,124 women, National Institutes of Health–AARP Study

Frequency of aspirin use in past 12 months


None
 <weekly
 1–6 times/week
 1+/day

Characteristic
 n
 %a
 n
 %a
 n
 %a
 n
 %a
Age at second questionnaire
     <57 years
 8,178
 19.0
 8,629
 21.7
 4,029
 20.1
 2,936
 13.3
     57–60 years
 8,317
 19.4
 8,211
 20.6
 4,022
 20.1
 3,566
 16.2
     61–64 years
 9,750
 22.7
 9,025
 22.7
 4,644
 23.2
 5,132
 23.2
     65–68 years
 11,085
 25.8
 9,459
 23.8
 4,881
 24.3
 6,607
 29.9
     69+ years
 5,630
 13.1
 4,457
 11.2
 2,481
 12.4
 3,839
 17.4
Race/ethnicity
     Caucasian/non-Hispanic white
 38,339
 89.2
 36,340
 91.4
 18,561
 92.5
 20,381
 92.3
     Other/unknown
 4,621
 10.8
 3,441
 8.6
 1,496
 7.5
 1,699
 7.7
Education
     <High school/high school grad
 13,537
 32.5
 10,675
 27.5
 5,769
 29.6
 6,857
 32.0
     Post-high school+
 28,171
 67.5
 28,110
 72.5
 13,696
 70.4
 14,554
 68.0
Body mass index at baseline
     <25 kg/m2
 18,461
 44.7
 18,855
 48.9
 9,040
 46.6
 8,718
 40.8
     25–30 kg/m2
 13,144
 31.8
 12,331
 32.0
 6,407
 33.0
 7,290
 34.2
     30+ kg/m2
 9,719
 23.5
 7,342
 19.1
 3,965
 20.4
 5,335
 25.0
Smoking
     Never
 19,321
 46.3
 18,123
 47.0
 8,996
 46.4
 8,984
 42.1
     Former
 16,758
 40.2
 15,314
 39.7
 7,735
 39.9
 9,184
 43.0
     Current
 5,630
 13.5
 5,137
 13.3
 2,656
 13.7
 3,193
 14.9
Alcoholic drinks
     0 drinks per day
 14,515
 33.8
 9,136
 23.0
 4,784
 23.9
 7,009
 31.7
     <1 drink per day
 23,322
 54.3
 24,771
 62.3
 12,299
 61.3
 12,111
 54.9
     1–3 drinks per day
 4,037
 9.4
 4,727
 11.9
 2,382
 11.9
 2,297
 10.4
     3+ drinks per day
 1,086
 2.5
 1,147
 2.9
 592
 3.0
 663
 3.0
Self-reported general health
     Excellent/very good/good
 36,189
 85.6
 36,638
 93.3
 17,869
 90.4
 17,868
 82.4
     Fair/poor
 6,094
 14.4
 2,639
 6.7
 1,891
 9.6
 3,814
 17.6
Stroke
     No
 42,293
 98.4
 39,557
 99.4
 19,844
 98.9
 21,112
 95.6
     Yes
 667
 1.6
 224
 0.6
 213
 1.1
 968
 4.4
Heart disease
     No
 39,820
 92.7
 38,292
 96.3
 18,924
 94.4
 17,561
 79.5
     Yes
 3,140
 7.3
 1,489
 3.7
 1,133
 5.6
 4,519
 20.5
High blood pressure
     No
 24,240
 60.2
 25,179
 67.7
 11,484
 61.5
 9,502
 46.1
     Yes
 16,001
 39.8
 11,997
 32.3
 7,192
 38.5
 11,117
 53.9
Mammogram in past 3 years
     Once or less
 13,226
 31.0
 12,161
 30.8
 6,043
 30.4
 6,496
 29.8
     Yes, more than once
 29,408
 69.0
 27,298
 69.2
 13,827
 69.6
 15,327
 70.2
Age at menarche
     <13 years
 21,222
 49.8
 18,850
 47.8
 9,679
 48.7
 11,036
 50.4
     13–14 years
 17,452
 41.0
 17,101
 43.4
 8,407
 42.3
 8,859
 40.5
     15+ years
 3,909
 9.2
 3,492
 8.9
 1,792
 9.0
 1,981
 9.1
Parity
     Nulliparous
 6,253
 14.8
 5,996
 15.3
 2,808
 14.2
 3,089
 14.3
     One
 4,459
 10.6
 4,056
 10.4
 2,009
 10.2
 2,172
 10.0
     Two
 11,052
 26.2
 10,488
 26.8
 5,290
 26.8
 5,406
 25.0
     Three or more
 20,431
 48.4
 18,578
 47.5
 9,608
 48.7
 10,987
 50.7
Age at first live birth
     Nulliparous
 6,253
 14.8
 5,996
 15.3
 2,808
 14.2
 3,089
 14.2
     <20 years
 7,385
 17.4
 6,016
 15.3
 3,319
 16.8
 3,895
 17.9
     20–24 years
 18,472
 43.6
 17,112
 43.6
 8,861
 44.9
 9,800
 45.1
     25–29 years
 7,636
 18.0
 7,582
 19.3
 3,632
 18.4
 3,739
 17.2
     30+ years
 2,575
 6.1
 2,499
 6.4
 1,129
 5.7
 1,191
 5.5
Age at menopause
     Premenopausal
 1,462
 3.4
 1,738
 4.4
 742
 3.7
 445
 2.0
     <45 years
 2,834
 6.6
 2,429
 6.1
 1,266
 6.3
 1,593
 7.2
     45–49 years
 6,543
 15.2
 6,316
 15.9
 2,997
 14.9
 3,358
 15.2
     50–54 years
 11,362
 26.4
 11,870
 29.8
 5,415
 27.0
 5,732
 26.0
     55+ years
 2,650
 6.2
 2,555
 6.4
 1,218
 6.1
 1,284
 5.8
     Surgical menopause
 16,770
 39.0
 13,577
 34.1
 7,754
 38.7
 8,975
 40.6
     Postmenopausal, age unknown
 1,339
 3.1
 1,296
 3.3
 665
 3.3
 693
 3.1
Hormone therapy formulation
     Never used
 17,328
 42.4
 15,676
 41.2
 7,201
 37.6
 8,371
 39.8
     Estrogen therapy only
 11,901
 29.1
 10,157
 26.7
 5,844
 30.5
 6,724
 32.0
     Estrogen–progestin therapy
 11,681
 28.6
 12,196
 32.1
 6,100
 31.9
 5,945
 28.3
Moderate/vigorous physical activity during past 10 years
     Never
 1,801
 4.3
 1,033
 2.6
 545
 2.8
 878
 4.0
     Rarely
 4,911
 11.6
 4,012
 10.2
 1,986
 10.1
 2,539
 11.7
     <1 hour/week
 4,473
 10.6
 4,102
 10.5
 2,107
 10.7
 2,347
 10.8
     1–3 hours/week
 10,495
 24.9
 10,085
 25.7
 5,240
 26.6
 5,457
 25.1
     4–7 hours/week
 10,379
 24.6
 10,438
 26.6
 5,311
 26.9
 5,371
 24.7
     >7 hours/week
 10,100
 24.0
 9,548
 24.3
 4,546
 23.0
 5,122
 23.6
Number breast biopsies
     None
 32,240
 75.8
 30,183
 76.6
 14,985
 75.4
 16,551
 75.8
     One
 6,819
 16.0
 6,175
 15.7
 3,217
 16.2
 3,428
 15.7
     Two
 1,904
 4.5
 1,666
 4.2
 926
 4.7
 997
 4.6
     Three or more
 1,581
 3.7
 1,360
 3.5
 737
 3.7
 863
 4.0
Family history of breast cancer in first degree relative (male or female)
     No
 29,536
 83.5
 27,782
 83.8
 13,814
 83.6
 14,930
 83.4
     Yes
 5,838
 16.5
 5,356
 16.2
 2,708
 16.4
 2,978
 16.6

aMissing values were excluded from percentage calculations.

Gierach et al. Breast Cancer Research 2008 10:R38   doi:10.1186/bcr2089