Table 2

Distribution of select risk factors across categories of nonaspirin nonsteroidal anti-inflammatory drug (NSAID) use among 126,124 women, National Institutes of Health–AARP Study

Frequency of nonaspirin NSAID use in past 12 months


None
 <weekly
 1–6 times/week
 1+/day

Characteristic
 n
 %a
 n
 %a
 n
 %a
 n
 %a
Age at second questionnaire
     <57 years
 7,112
 14.3
 9,185
 23.4
 4,563
 24.0
 2,955
 17.9
     57–60 years
 8,605
 17.3
 8,288
 21.1
 4,171
 21.9
 3,052
 18.4
     61–64 years
 11,482
 23.0
 8,854
 22.5
 4,278
 22.5
 3,876
 23.4
     65–68 years
 14,666
 29.4
 8,841
 22.5
 4,039
 21.2
 4,399
 26.6
     69+ years
 7,962
 16.0
 4,136
 10.5
 1,962
 10.3
 2,263
 13.7
Race/ethnicity
     Caucasian/non-Hispanic white
 44,909
 90.1
 35,940
 91.4
 17,537
 92.2
 15,103
 91.3
     Other/unknown
 4,918
 9.9
 3,364
 8.6
 1,476
 7.8
 1,442
 8.7
Education
     <High school/high school grad
 16,007
 33.1
 10,402
 27.1
 5,595
 30.3
 4,734
 29.5
     Post-high school+
 32,364
 66.9
 27,959
 72.9
 12,851
 69.7
 11,312
 70.5
Body mass index at baseline
     <25 kg/m2
 23,279
 48.6
 18,527
 48.6
 7,800
 42.4
 5,418
 33.9
     25–30 kg/m2
 15,189
 31.7
 12,423
 32.6
 6,194
 33.7
 5,296
 33.2
     30+ kg/m2
 9,464
 19.7
 7,193
 18.9
 4,413
 24.0
 5,254
 32.9
Smoking
     Never
 22,702
 47.0
 17,354
 45.5
 8,254
 44.8
 7,062
 44.0
     Former
 18,554
 38.4
 15,751
 41.3
 7,708
 41.9
 6,942
 43.2
     Current
 7,025
 14.6
 5,023
 13.2
 2,453
 13.3
 2,050
 12.8
Alcoholic drinks
     0 drinks per day
 16,225
 32.6
 9,230
 23.5
 4,728
 24.9
 5,121
 31.0
     <1 drink per day
 27,087
 54.4
 24,388
 62.0
 11,660
 61.3
 9,312
 56.3
     1–3 drinks per day
 5,108
 10.3
 4,570
 11.6
 2,153
 11.3
 1,616
 9.8
     3+ drinks per day
 1,407
 2.8
 1,116
 2.8
 472
 2.5
 496
 3.0
Self-reported general health
     Excellent/very good/good
 42,891
 87.5
 35,824
 92.4
 16,655
 88.8
 13,073
 80.5
     Fair/poor
 6,142
 12.5
 2,966
 7.6
 2,106
 11.2
 3,176
 19.5
Stroke
     No
 48,762
 97.9
 38,882
 98.9
 18,760
 98.7
 16,223
 98.1
     Yes
 1,065
 2.1
 422
 1.1
 253
 1.3
 322
 1.9
Heart disease
     No
 44,964
 90.2
 36,916
 93.9
 17,658
 92.9
 14,936
 90.3
     Yes
 4,863
 9.8
 2,388
 6.1
 1,355
 7.1
 1,609
 9.7
High blood pressure
     No
 27,666
 59.6
 23,960
 65.1
 10,656
 60.1
 8,036
 51.7
     Yes
 18,783
 40.4
 12,847
 34.9
 7,080
 39.9
 7,508
 48.3
Mammogram in past 3 years
     Once or less
 17,403
 35.3
 10,768
 27.6
 5,095
 27.0
 4,509
 27.5
     Yes, more than once
 31,949
 64.7
 28,229
 72.4
 13,749
 73.0
 11,904
 72.5
Age at menarche
     <13 years
 23,714
 48.1
 18,717
 48.0
 9,436
 50.0
 8,816
 53.7
     13–14 years
 21,018
 42.6
 16,749
 43.0
 7,752
 41.1
 6,269
 38.2
     15+ years
 4,604
 9.3
 3,516
 9.0
 1,685
 8.9
 1,336
 8.1
Parity
     Nulliparous
 8,010
 16.4
 5,540
 14.3
 2,375
 12.7
 2,212
 13.6
     One
 5,330
 10.9
 4,022
 10.4
 1,794
 9.6
 1,546
 9.5
     Two
 12,441
 25.5
 10,535
 27.2
 5,125
 27.3
 4,095
 25.2
     Three or more
 23,059
 47.2
 18,566
 48.0
 9,445
 50.4
 8,418
 51.7
Age at first live birth
     Nulliparous
 8,010
 16.4
 5,540
 14.3
 2,375
 12.6
 2,212
 13.6
     <20 years
 7,690
 15.7
 6,056
 15.6
 3,559
 19.0
 3,229
 19.8
     20–24 years
 21,059
 43.0
 17,194
 44.4
 8,585
 45.7
 7,350
 45.1
     25–29 years
 9,058
 18.5
 7,520
 19.4
 3,310
 17.6
 2,676
 16.4
     30+ years
 3,153
 6.4
 2,439
 6.3
 948
 5.0
 844
 5.2
Age at menopause
     Premenopausal
 1,145
 2.3
 1,864
 4.7
 886
 4.7
 487
 2.9
     <45 years
 3,654
 7.3
 2,377
 6.0
 1,063
 5.6
 995
 6.0
     45–49 years
 8,216
 16.5
 5,941
 15.1
 2,732
 14.4
 2,288
 13.8
     50–54 years
 14,355
 28.8
 11,383
 29.0
 4,705
 24.7
 3,895
 23.5
     55+ years
 3,209
 6.4
 2,519
 6.4
 1,019
 5.4
 945
 5.7
     Surgical menopause
 17,713
 35.5
 13,938
 35.5
 7,962
 41.9
 7,430
 44.9
Postmenopausal, age unknown
 1,535
 3.1
 1,282
 3.3
 646
 3.4
 505
 3.1
Hormone therapy formulation
     Never used
 23,083
 48.6
 14,199
 37.8
 5,961
 32.9
 5,179
 32.8
     Estrogen therapy only
 12,664
 26.7
 10,499
 27.9
 5,910
 32.7
 5,522
 35.0
     Estrogen–progestin therapy
 11,762
 24.8
 12,876
 34.3
 6,224
 34.4
 5,072
 32.2
Moderate/vigorous physical activity during past 10 years
     Never
 1,922
 3.9
 1,004
 2.6
 551
 2.9
 749
 4.6
     Rarely
 5,434
 11.1
 3,953
 10.2
 1,993
 10.6
 2,032
 12.5
     <1 hour/week
 5,034
 10.3
 4,196
 10.8
 1,980
 10.6
 1,815
 11.2
     1–3 hours/week
 12,127
 24.8
 10,252
 26.4
 4,815
 25.7
 4,091
 25.2
     4–7 hours/week
 12,378
 25.3
 10,169
 26.2
 4,981
 26.6
 3,924
 24.1
     >7 hours/week
 12,017
 24.6
 9,234
 23.8
 4,397
 23.5
 3,642
 22.4
Number breast biopsies
     None
 37,903
 76.9
 29,547
 75.9
 14,113
 74.9
 12,243
 74.7
     One
 7,549
 15.3
 6,236
 16.0
 3,114
 16.5
 2,727
 16.6
     Two
 2,042
 4.1
 1,779
 4.6
 884
 4.7
 768
 4.7
     Three or more
 1,793
 3.6
 1,373
 3.5
 743
 3.9
 652
 4.0
Family history of breast cancer in first degree relative (male or female)
     No
 33,976
 83.6
 27,478
 83.7
 13,197
 83.8
 11,295
 82.8
     Yes
 6,643
 16.4
 5,346
 16.3
 2,554
 16.2
 2,347
 17.2

aMissing values were excluded from percentage calculations.

Gierach et al. Breast Cancer Research 2008 10:R38   doi:10.1186/bcr2089