Breast Cancer Research | Volume 10 Issue 3

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	Volume 10 Issue 3
	Comment
	Editorial SELDI-TOF proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression Bashar A Zeidan, Paul A Townsend Breast Cancer Research 2008, 10:107 (30 June 2008) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Alternative splicing and the progesterone receptor in breast cancer David MW Cork, Thomas WJ Lennard, Alison J Tyson-Capper Breast Cancer Research 2008, 10:207 (30 May 2008) Abstract \| Full text \| PDF \| PubMed
	Review Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories? Graham B Byrnes, Melissa C Southey, John L Hopper Breast Cancer Research 2008, 10:208 (5 June 2008) Abstract \| Full text \| PDF \| PubMed
	Review Mammographic density. Measurement of mammographic density Martin J Yaffe Breast Cancer Research 2008, 10:209 (19 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism Vasilis Androutsopoulos, Randolph RJ Arroo, John F Hall, Somchaiya Surichan, Gerry A Potter Breast Cancer Research 2008, 10:R39 (2 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The flavone eupatorin, found in certain plants and used in folk medicine, selectively inhibits the growth of breast carcinoma cells through CYP1 family mediated metabolism, making it a potential chemopreventative candidate.
	Research article Autoantibodies as potential biomarkers for breast cancer Li Zhong, Kun Ge, Jin-chi Zu, Long-hua Zhao, Wei-ke Shen, Jian-fei Wang, Xiao-gang Zhang, Xu Gao, Wanping Hu, Yun Yen, Kemp H Kernstine Breast Cancer Research 2008, 10:R40 (7 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Serum autoantibody profiling is a promising approach for early detection and diagnosis of breast cancer, and a panel of autoantibodies appears preferable to achieve superior accuracy.
	Research article Breast cancer tumor growth estimated through mammography screening data Harald Weedon-Fekjær, Bo H Lindqvist, Lars J Vatten, Odd O Aalen, Steinar Tretli Breast Cancer Research 2008, 10:R41 (8 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A new model which can estimate the growth rate of breast cancer, as well as the proportion of tumors detected at screening, shows slower growth rates with increasing age.
	Research article Intact and total insulin-like growth factor-binding protein-3 (IGFBP-3) levels in relation to breast cancer risk factors: a cross-sectional study Caroline Diorio, Jacques Brisson, Sylvie Bérubé, Michael Pollak Breast Cancer Research 2008, 10:R42 (9 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53^+/-mice Karen A Dunphy, Anneke C Blackburn, Haoheng Yan, Lauren R O'Connell, D Joseph Jerry Breast Cancer Research 2008, 10:R43 (12 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article TIMP-2 mediates the anti-invasive effects of the nitric oxide-releasing prodrug JS-K in breast cancer cells Ann-Marie Simeone, Vanity McMurtry, René Nieves-Alicea, Joseph E Saavedra, Larry K Keefer, Marcella M Johnson, Ana M Tari Breast Cancer Research 2008, 10:R44 (12 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer Brian M Nolen, Jeffrey R Marks, Shlomo Ta'san, Alex Rand, The Luong, Yun Wang, Kimberly Blackwell, Anna E Lokshin Breast Cancer Research 2008, 10:R45 (12 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors Eiji Sunami, Masaru Shinozaki, Myung-Shin Sim, Sandy L Nguyen, Anh-Thu Vu, Armando E Giuliano, Dave SB Hoon Breast Cancer Research 2008, 10:R46 (16 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort Elizabeth M Azzato, Kristy E Driver, Fabienne Lesueur, Mitul Shah, David Greenberg, Douglas F Easton, Andrew E Teschendorff, Carlos Caldas, Neil E Caporaso, Paul DP Pharoah Breast Cancer Research 2008, 10:R47 (28 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression Kristyna Brozkova, Eva Budinska, Pavel Bouchal, Lenka Hernychova, Dana Knoflickova, Dalibor Valik, Rostislav Vyzula, Borivoj Vojtesek, Rudolf Nenutil Breast Cancer Research 2008, 10:R48 (29 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary SELDI-TOF mass spectometry profiling produces similar clustering of tumours to microarray-based gene expression profiling, and has the potential to identify novel biomarkers and produce clinically useful classifications of breast carcinomas.
	Research article Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas Christina Magkou, Lydia Nakopoulou, Christina Zoubouli, Kanelina Karali, Irene Theohari, Panagiotis Bakarakos, Ioanna Giannopoulou Breast Cancer Research 2008, 10:R49 (3 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Mammary carcinoma behavior is programmed in the precancer stem cell Patrizia Damonte, J Graeme Hodgson, Jane Chen, Lawrence JT Young, Robert D Cardiff, Alexander D Borowsky Breast Cancer Research 2008, 10:R50 (3 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Studies in a mouse model establish a "pre-cancer" stem cell as the origin of invasive cancer, suggesting the risk of advancing to invasive breast cancer may be predictable at the precancer stage.
	Research article Jab1 is a target of EGFR signaling in ERα-negative breast cancer Jiaxu Wang, Rebecca O Barnes, Nathan R West, Melanie Olson, Jenny E Chu, Peter H Watson Breast Cancer Research 2008, 10:R51 (6 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells Matthew J Grimshaw, Lucienne Cooper, Konstantinos Papazisis, Julia A Coleman, Hermann R Bohnenkamp, Laura Chiapero-Stanke, Joyce Taylor-Papadimitriou, Joy M Burchell Breast Cancer Research 2008, 10:R52 (9 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mammosphere culture of metastatic cells from pleural effusions enriches for tumour-inducing cells, and could represent a novel model for studying tumorigenic 'stem' cell sensitivity to therapeutic agents.
	Research article The CD44⁺/CD24^-phenotype is enriched in basal-like breast tumors Gabriella Honeth, Pär-Ola Bendahl, Markus Ringnér, Lao H Saal, Sofia K Gruvberger-Saal, Kristina Lövgren, Dorthe Grabau, Mårten Fernö, Åke Borg, Cecilia Hegardt Breast Cancer Research 2008, 10:R53 (17 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Basal-like and particularly BRCA1 hereditary breast cancer are associated with CD44+/CD24- cells, however tumorigenicity may not be confined to cells of this phenotype as they are found in very few HER2+ tumours.
	Research article PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes Anna Git, Inmaculada Spiteri, Cherie Blenkiron, Mark J Dunning, Jessica CM Pole, Suet-Feung Chin, Yanzhong Wang, James Smith, Frederick J Livesey, Carlos Caldas Breast Cancer Research 2008, 10:R54 (27 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Breast cancer cell line PMC42 is a good model for normal breast epithelium, providing a unique biological tool to study breast differentiation and the function of key miRNAs typically lost in cancer.
	Correspondence
	Letter The future of mammary stem cell biology: the power of in vivo transplants Geoffrey J Lindeman, Jane E Visvader, Matthew J Smalley, Connie J Eaves Breast Cancer Research 2008, 10:402 (29 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter The future of mammary stem cell biology: the power of in vivo transplants – authors' response Gilbert H Smith, Daniel Medina Breast Cancer Research 2008, 10:403 (29 May 2008) Abstract \| Full text \| PDF

	Volume 10 Issue 3
	Comment
	Editorial SELDI-TOF proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression Bashar A Zeidan, Paul A Townsend Breast Cancer Research 2008, 10:107 (30 June 2008) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Alternative splicing and the progesterone receptor in breast cancer David MW Cork, Thomas WJ Lennard, Alison J Tyson-Capper Breast Cancer Research 2008, 10:207 (30 May 2008) Abstract \| Full text \| PDF \| PubMed
	Review Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories? Graham B Byrnes, Melissa C Southey, John L Hopper Breast Cancer Research 2008, 10:208 (5 June 2008) Abstract \| Full text \| PDF \| PubMed
	Review Mammographic density. Measurement of mammographic density Martin J Yaffe Breast Cancer Research 2008, 10:209 (19 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism Vasilis Androutsopoulos, Randolph RJ Arroo, John F Hall, Somchaiya Surichan, Gerry A Potter Breast Cancer Research 2008, 10:R39 (2 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The flavone eupatorin, found in certain plants and used in folk medicine, selectively inhibits the growth of breast carcinoma cells through CYP1 family mediated metabolism, making it a potential chemopreventative candidate.
	Research article Autoantibodies as potential biomarkers for breast cancer Li Zhong, Kun Ge, Jin-chi Zu, Long-hua Zhao, Wei-ke Shen, Jian-fei Wang, Xiao-gang Zhang, Xu Gao, Wanping Hu, Yun Yen, Kemp H Kernstine Breast Cancer Research 2008, 10:R40 (7 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Serum autoantibody profiling is a promising approach for early detection and diagnosis of breast cancer, and a panel of autoantibodies appears preferable to achieve superior accuracy.
	Research article Breast cancer tumor growth estimated through mammography screening data Harald Weedon-Fekjær, Bo H Lindqvist, Lars J Vatten, Odd O Aalen, Steinar Tretli Breast Cancer Research 2008, 10:R41 (8 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A new model which can estimate the growth rate of breast cancer, as well as the proportion of tumors detected at screening, shows slower growth rates with increasing age.
	Research article Intact and total insulin-like growth factor-binding protein-3 (IGFBP-3) levels in relation to breast cancer risk factors: a cross-sectional study Caroline Diorio, Jacques Brisson, Sylvie Bérubé, Michael Pollak Breast Cancer Research 2008, 10:R42 (9 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53^+/-mice Karen A Dunphy, Anneke C Blackburn, Haoheng Yan, Lauren R O'Connell, D Joseph Jerry Breast Cancer Research 2008, 10:R43 (12 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article TIMP-2 mediates the anti-invasive effects of the nitric oxide-releasing prodrug JS-K in breast cancer cells Ann-Marie Simeone, Vanity McMurtry, René Nieves-Alicea, Joseph E Saavedra, Larry K Keefer, Marcella M Johnson, Ana M Tari Breast Cancer Research 2008, 10:R44 (12 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer Brian M Nolen, Jeffrey R Marks, Shlomo Ta'san, Alex Rand, The Luong, Yun Wang, Kimberly Blackwell, Anna E Lokshin Breast Cancer Research 2008, 10:R45 (12 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors Eiji Sunami, Masaru Shinozaki, Myung-Shin Sim, Sandy L Nguyen, Anh-Thu Vu, Armando E Giuliano, Dave SB Hoon Breast Cancer Research 2008, 10:R46 (16 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort Elizabeth M Azzato, Kristy E Driver, Fabienne Lesueur, Mitul Shah, David Greenberg, Douglas F Easton, Andrew E Teschendorff, Carlos Caldas, Neil E Caporaso, Paul DP Pharoah Breast Cancer Research 2008, 10:R47 (28 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression Kristyna Brozkova, Eva Budinska, Pavel Bouchal, Lenka Hernychova, Dana Knoflickova, Dalibor Valik, Rostislav Vyzula, Borivoj Vojtesek, Rudolf Nenutil Breast Cancer Research 2008, 10:R48 (29 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary SELDI-TOF mass spectometry profiling produces similar clustering of tumours to microarray-based gene expression profiling, and has the potential to identify novel biomarkers and produce clinically useful classifications of breast carcinomas.
	Research article Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas Christina Magkou, Lydia Nakopoulou, Christina Zoubouli, Kanelina Karali, Irene Theohari, Panagiotis Bakarakos, Ioanna Giannopoulou Breast Cancer Research 2008, 10:R49 (3 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Mammary carcinoma behavior is programmed in the precancer stem cell Patrizia Damonte, J Graeme Hodgson, Jane Chen, Lawrence JT Young, Robert D Cardiff, Alexander D Borowsky Breast Cancer Research 2008, 10:R50 (3 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Studies in a mouse model establish a "pre-cancer" stem cell as the origin of invasive cancer, suggesting the risk of advancing to invasive breast cancer may be predictable at the precancer stage.
	Research article Jab1 is a target of EGFR signaling in ERα-negative breast cancer Jiaxu Wang, Rebecca O Barnes, Nathan R West, Melanie Olson, Jenny E Chu, Peter H Watson Breast Cancer Research 2008, 10:R51 (6 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells Matthew J Grimshaw, Lucienne Cooper, Konstantinos Papazisis, Julia A Coleman, Hermann R Bohnenkamp, Laura Chiapero-Stanke, Joyce Taylor-Papadimitriou, Joy M Burchell Breast Cancer Research 2008, 10:R52 (9 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mammosphere culture of metastatic cells from pleural effusions enriches for tumour-inducing cells, and could represent a novel model for studying tumorigenic 'stem' cell sensitivity to therapeutic agents.
	Research article The CD44⁺/CD24^-phenotype is enriched in basal-like breast tumors Gabriella Honeth, Pär-Ola Bendahl, Markus Ringnér, Lao H Saal, Sofia K Gruvberger-Saal, Kristina Lövgren, Dorthe Grabau, Mårten Fernö, Åke Borg, Cecilia Hegardt Breast Cancer Research 2008, 10:R53 (17 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Basal-like and particularly BRCA1 hereditary breast cancer are associated with CD44+/CD24- cells, however tumorigenicity may not be confined to cells of this phenotype as they are found in very few HER2+ tumours.
	Research article PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes Anna Git, Inmaculada Spiteri, Cherie Blenkiron, Mark J Dunning, Jessica CM Pole, Suet-Feung Chin, Yanzhong Wang, James Smith, Frederick J Livesey, Carlos Caldas Breast Cancer Research 2008, 10:R54 (27 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Breast cancer cell line PMC42 is a good model for normal breast epithelium, providing a unique biological tool to study breast differentiation and the function of key miRNAs typically lost in cancer.
	Correspondence
	Letter The future of mammary stem cell biology: the power of in vivo transplants Geoffrey J Lindeman, Jane E Visvader, Matthew J Smalley, Connie J Eaves Breast Cancer Research 2008, 10:402 (29 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter The future of mammary stem cell biology: the power of in vivo transplants – authors' response Gilbert H Smith, Daniel Medina Breast Cancer Research 2008, 10:403 (29 May 2008) Abstract \| Full text \| PDF

Explore journal

Articles

Volume 10 Issue 3

Comment

Review

Research

Correspondence