Additional file 1.

Additional file 1 is a Word document containing calculations, based on a logistic model for lifetime risk of breast cancer, of the FRR resulting from a given number of alleles of specified per-allele odds-ratio and allele frequency. It also contains calculations of the number of SNPs required to produce a typical FRR.

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Byrnes et al. Breast Cancer Research 2008 10:208   doi:10.1186/bcr2099