Table 3

Predictive power of multimarker panels

Panel

Timepoint

Response type

Sensitivity (%)

Specificity (%)

α-Fetoprotein, soluble vascular cell adhesion molecule 1, MMP-9

Pretreatment

Clinical complete response versus no response

83

91

Tissue plasminogen activator inhibitor 1

Pretreatment

Clinical complete response/clinical partial response versus no response

75

77

MMP-3, luteinizing hormone, thyroid-stimulating hormone

Pre-cycle 2

Clinical complete response versus no response

82

73

ErbB2, epidermal growth factor receptor, migration inhibitory factor, MMP-2, CD40 ligand

Pre-cycle 2

Pathologic complete response/pathologic partial response versus no response

85

69

Nolen et al. Breast Cancer Research 2008 10:R45   doi:10.1186/bcr2096