Table 4

Comparison of primary tumor gene methylation status relative to ER status

Gene
ER negative (n = 65)
ER positive (n = 65)
P valuea




n
%
n
%


RASSF1A
36
55%
60
92%
<0.0001
CCND2
26
40%
45
69%
0.0008
GSTP1
4
6%
19
29%
0.0006
TWIST
17
26%
32
49%
0.0066
APC
20
31%
31
48%
0.048
NES1
13
20%
22
34%
NS
RARβ2
18
28%
17
26%
NS
CDH1
53
82%
54
83%
NS

aχ2 test or Fisher's exact test was used appropriately. ER, estrogen receptor; NS, not significant.

Sunami et al. Breast Cancer Research 2008 10:R46   doi:10.1186/bcr2098