|
SEARCH participant survival characteristics |
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| Set 1 |
Sets 1 and 2 |
|||
| n = 2,270 |
n = 4,470 |
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|
|
||||
| Total time at risk, years |
1,3851.47 |
2,5049.24 |
||
| Median follow-up, yearsa |
7.75 |
(0.56–10)b |
7.45 |
(0.48–10)b |
| Median time at risk, years |
6.47 |
(0.10–9.64)b |
5.70 |
(0.03–9.77)b |
| Median time from diagnosis to study entry, years |
0.73 |
(0.00–8.64)b |
1.16 |
(0.00–9.34)b |
| Number of deaths |
359 |
637 |
||
| Annual mortality rate |
0.026 |
0.025 |
||
| 5-year survival rate |
0.88 |
(0.86–0.89)c |
0.88 |
(0.87–0.89)c |
| Median age at diagnosis, years |
50.2 |
(25–69)b |
51.0 |
(23–69)b |
| Age at diagnosis, years |
||||
| <40 |
212 |
9.30% |
394 |
8.81% |
| 40–49 |
753 |
33.20% |
1,331 |
29.78% |
| 50–59 |
997 |
43.90% |
1,802 |
40.31% |
| 60+ |
308 |
13.60% |
943 |
21.10% |
| Histopathological grade |
||||
| Well differentiated |
434 |
19.11% |
871 |
19.49% |
| Moderately differentiated |
787 |
34.67% |
1,687 |
37.74% |
| Poorly differentiated |
504 |
22.20% |
1,019 |
22.80% |
| Unknown |
545 |
24.00% |
893 |
19.98% |
| Morphological type |
||||
| Ductal |
1,674 |
73.74% |
3,316 |
74.18% |
| Lobular |
351 |
15.46% |
659 |
14.74% |
| Other |
222 |
9.78% |
455 |
10.17% |
| Unknown |
23 |
1.01% |
40 |
0.89% |
| Clinical stage |
||||
| 1 |
1,112 |
48.99% |
2,190 |
48.99% |
| 2 |
986 |
43.33% |
1,981 |
44.32% |
| 3 or 4 |
172 |
7.58% |
194 |
4.34% |
| Missing |
0 |
0% |
105 |
2.35% |
|
aFollow-up censored at 10 years. bRange of variable. c95% confidence interval. SEARCH, Studies of Epidemiology and Risk factors in Cancer Heredity. | ||||
Azzato et al. Breast Cancer Research 2008 10:R47 doi:10.1186/bcr2100 |
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