Breast Cancer Research | Volume 10 Issue 4

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Articles

	Volume 10 Issue 4
	Comment
	Viewpoint Regulation of cancer stem cells by p53 D Joseph Jerry, Luwei Tao, Haoheng Yan Breast Cancer Research 2008, 10:304 (29 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Variation in breast cancer risk in BRCA1 and BRCA2 mutation carriers Timothy R Rebbeck, Susan M Domchek Breast Cancer Research 2008, 10:108 (25 July 2008) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Breast cancer stem cells: implications for therapy of breast cancer Brian J Morrison, Chris W Schmidt, Sunil R Lakhani, Brent A Reynolds, J Alejandro Lopez Breast Cancer Research 2008, 10:210 (22 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Molecular targeted therapies for breast cancer treatment Claus M Schlotter, Ulf Vogt, Heike Allgayer, Burkhard Brandt Breast Cancer Research 2008, 10:211 (24 July 2008) Abstract \| Full text \| PDF \| PubMed
	Review Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer Mustafa Akkiprik, Yumei Feng, Huamin Wang, Kexin Chen, Limei Hu, Aysegul Sahin, Savitri Krishnamurthy, Ayse Ozer, Xishan Hao, Wei Zhang Breast Cancer Research 2008, 10:212 (11 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Risk prediction models with incomplete data with application to prediction of estrogen receptor-positive breast cancer: prospective data from the Nurses' Health Study Bernard Rosner, Graham A Colditz, J Dirk Iglehart, Susan E Hankinson Breast Cancer Research 2008, 10:R55 (3 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Serum estradiol levels in postmenopausal women appear to add to other lifestyle factors in predicting a woman’s individual risk of breast cancer and may contribute significantly to current risk prediction models.
	Research article The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer Joanna Lisztwan, Astrid Pornon, Bin Chen, Shiuan Chen, Dean B Evans Breast Cancer Research 2008, 10:R56 (8 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II Heather Feigelson, Lauren R Teras, W Ryan Diver, Weining Tang, Alpa V Patel, Victoria L Stevens, Eugenia E Calle, Michael J Thun, Mark Bouzyk Breast Cancer Research 2008, 10:R57 (8 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer Nuran Bektas, Erik Noetzel, Jürgen Veeck, Michael F Press, Glen Kristiansen, Amjad Naami, Arndt Hartmann, Arno Dimmler, Matthias W Beckmann, Ruth Knüchel, Peter A Fasching, Edgar Dahl Breast Cancer Research 2008, 10:R58 (15 July 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical Asian country (Malaysia) with a relatively low incidence of breast cancer E Thirthagiri, SY Lee, P Kang, DS Lee, GT Toh, S Selamat, S-Y Yoon, NA Mohd Taib, MK Thong, CH Yip, SH Teo Breast Cancer Research 2008, 10:R59 (16 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Evaluation of BRCA mutation testing in an Asian population highlights the need for validation of current breast cancer risk prediction models for non-Caucasian populations so they may benefit from genetic testing.
	Research article Continuing trastuzumab beyond disease progression: outcomes analysis in patients with metastatic breast cancer Giuseppe Cancello, Emilia Montagna, Diego D'Agostino, Mario Giuliano, Antonio Giordano, Giuseppe Di Lorenzo, Monica Plaitano, Sabino De Placido, Michele De Laurentiis Breast Cancer Research 2008, 10:R60 (16 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers Christina Yau, Christopher C Benz Breast Cancer Research 2008, 10:R61 (17 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An investigation into the effect of oxidative stress on estrogen and estrogen receptor-regulated gene expression identified a subset of oxidant-sensitive genes associated with poor prognosis in ER+ primary breast cancer.
	Research article Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays David I Rodenhiser, Joseph Andrews, Wendy Kennette, Bekim Sadikovic, Ariel Mendlowitz, Alan B Tuck, Ann F Chambers Breast Cancer Research 2008, 10:R62 (18 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Over-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer Shirly Davidovich, Ofer Ben-Izhak, Ma'anit Shapira, Boris Futerman, Dan D Hershko Breast Cancer Research 2008, 10:R63 (21 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Skp2 expression, associated with poor prognosis, may be a useful marker for predicting response to doxorubicin-based preoperative chemotherapy and clinical outcome in patients with locally advanced breast cancer.
	Research article Visually assessed breast density, breast cancer risk and the importance of the craniocaudal view Stephen W Duffy, Iris D Nagtegaal, Susan M Astley, Maureen GC Gillan, Magnus A McGee, Caroline RM Boggis, Mary Wilson, Ursula M Beetles, Miriam A Griffiths, Anil K Jain, Jill Johnson, Rita Roberts, Heather Deans, Karen A Duncan, Geeta Iyengar, Pam M Griffiths, Jane Warwick, Jack Cuzick, Fiona J Gilbert Breast Cancer Research 2008, 10:R64 (23 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Visually assessed breast density can predict breast cancer risk as well as density measured using the ‘gold standard’ labour-intensive interactive threshold software when two views, including the craniocaudal view, are available.
	Research article Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures Pratyaksha Wirapati, Christos Sotiriou, Susanne Kunkel, Pierre Farmer, Sylvain Pradervand, Benjamin Haibe-Kains, Christine Desmedt, Michail Ignatiadis, Thierry Sengstag, Frédéric Schütz, Darlene R Goldstein, Martine Piccart, Mauro Delorenzi Breast Cancer Research 2008, 10:R65 (28 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Breast cancer susceptibility loci and mammographic density Rulla M Tamimi, David Cox, Peter Kraft, Graham A Colditz, Susan E Hankinson, David J Hunter Breast Cancer Research 2008, 10:R66 (5 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer Rulla M Tamimi, Heather J Baer, Jonathan Marotti, Mark Galan, Laurie Galaburda, Yineng Fu, Anne C Deitz, James L Connolly, Stuart J Schnitt, Graham A Colditz, Laura C Collins Breast Cancer Research 2008, 10:R67 (5 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity Sacha J Howell, Elizabeth Anderson, Tom Hunter, Gillian Farnie, Robert B Clarke Breast Cancer Research 2008, 10:R68 (5 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Enrichment with anti-cytokeratin alone or combined with anti-EpCAM antibodies significantly increases the sensitivity for circulating tumor cell detection in metastatic breast cancer patients Glenn Deng, Michael Herrler, David Burgess, Edward Manna, David Krag, Julian F Burke Breast Cancer Research 2008, 10:R69 (7 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3 Christian D Young, Erica C Nolte, Andrew Lewis, Natalie J Serkova, Steven M Anderson Breast Cancer Research 2008, 10:R70 (13 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells Yvonne Radestock, Cuong Hoang-Vu, Sabine Hombach-Klonisch Breast Cancer Research 2008, 10:R71 (21 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Variable size computer-aided detection prompts and mammography film reader decisions Fiona J Gilbert, Susan M Astley, Caroline RM Boggis, Magnus A McGee, Pamela M Griffiths, Stephen W Duffy, Olorunsola F Agbaje, Maureen GC Gillan, Mary Wilson, Anil K Jain, Nicola Barr, Ursula M Beetles, Miriam A Griffiths, Jill Johnson, Rita M Roberts, Heather E Deans, Karen A Duncan, Geeta Iyengar Breast Cancer Research 2008, 10:R72 (25 August 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Prompted mammograms, where computer-aided detection systems alert readers to suspicious features, result in more recalls for both normal and cancer cases, and variable size prompts may be most useful.
	Research article A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast cancer Andrew E Teschendorff, Carlos Caldas Breast Cancer Research 2008, 10:R73 (28 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

	Volume 10 Issue 4
	Comment
	Viewpoint Regulation of cancer stem cells by p53 D Joseph Jerry, Luwei Tao, Haoheng Yan Breast Cancer Research 2008, 10:304 (29 August 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Variation in breast cancer risk in BRCA1 and BRCA2 mutation carriers Timothy R Rebbeck, Susan M Domchek Breast Cancer Research 2008, 10:108 (25 July 2008) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Breast cancer stem cells: implications for therapy of breast cancer Brian J Morrison, Chris W Schmidt, Sunil R Lakhani, Brent A Reynolds, J Alejandro Lopez Breast Cancer Research 2008, 10:210 (22 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Molecular targeted therapies for breast cancer treatment Claus M Schlotter, Ulf Vogt, Heike Allgayer, Burkhard Brandt Breast Cancer Research 2008, 10:211 (24 July 2008) Abstract \| Full text \| PDF \| PubMed
	Review Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer Mustafa Akkiprik, Yumei Feng, Huamin Wang, Kexin Chen, Limei Hu, Aysegul Sahin, Savitri Krishnamurthy, Ayse Ozer, Xishan Hao, Wei Zhang Breast Cancer Research 2008, 10:212 (11 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Risk prediction models with incomplete data with application to prediction of estrogen receptor-positive breast cancer: prospective data from the Nurses' Health Study Bernard Rosner, Graham A Colditz, J Dirk Iglehart, Susan E Hankinson Breast Cancer Research 2008, 10:R55 (3 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Serum estradiol levels in postmenopausal women appear to add to other lifestyle factors in predicting a woman’s individual risk of breast cancer and may contribute significantly to current risk prediction models.
	Research article The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer Joanna Lisztwan, Astrid Pornon, Bin Chen, Shiuan Chen, Dean B Evans Breast Cancer Research 2008, 10:R56 (8 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II Heather Feigelson, Lauren R Teras, W Ryan Diver, Weining Tang, Alpa V Patel, Victoria L Stevens, Eugenia E Calle, Michael J Thun, Mark Bouzyk Breast Cancer Research 2008, 10:R57 (8 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer Nuran Bektas, Erik Noetzel, Jürgen Veeck, Michael F Press, Glen Kristiansen, Amjad Naami, Arndt Hartmann, Arno Dimmler, Matthias W Beckmann, Ruth Knüchel, Peter A Fasching, Edgar Dahl Breast Cancer Research 2008, 10:R58 (15 July 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical Asian country (Malaysia) with a relatively low incidence of breast cancer E Thirthagiri, SY Lee, P Kang, DS Lee, GT Toh, S Selamat, S-Y Yoon, NA Mohd Taib, MK Thong, CH Yip, SH Teo Breast Cancer Research 2008, 10:R59 (16 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Evaluation of BRCA mutation testing in an Asian population highlights the need for validation of current breast cancer risk prediction models for non-Caucasian populations so they may benefit from genetic testing.
	Research article Continuing trastuzumab beyond disease progression: outcomes analysis in patients with metastatic breast cancer Giuseppe Cancello, Emilia Montagna, Diego D'Agostino, Mario Giuliano, Antonio Giordano, Giuseppe Di Lorenzo, Monica Plaitano, Sabino De Placido, Michele De Laurentiis Breast Cancer Research 2008, 10:R60 (16 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers Christina Yau, Christopher C Benz Breast Cancer Research 2008, 10:R61 (17 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An investigation into the effect of oxidative stress on estrogen and estrogen receptor-regulated gene expression identified a subset of oxidant-sensitive genes associated with poor prognosis in ER+ primary breast cancer.
	Research article Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays David I Rodenhiser, Joseph Andrews, Wendy Kennette, Bekim Sadikovic, Ariel Mendlowitz, Alan B Tuck, Ann F Chambers Breast Cancer Research 2008, 10:R62 (18 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Over-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer Shirly Davidovich, Ofer Ben-Izhak, Ma'anit Shapira, Boris Futerman, Dan D Hershko Breast Cancer Research 2008, 10:R63 (21 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Skp2 expression, associated with poor prognosis, may be a useful marker for predicting response to doxorubicin-based preoperative chemotherapy and clinical outcome in patients with locally advanced breast cancer.
	Research article Visually assessed breast density, breast cancer risk and the importance of the craniocaudal view Stephen W Duffy, Iris D Nagtegaal, Susan M Astley, Maureen GC Gillan, Magnus A McGee, Caroline RM Boggis, Mary Wilson, Ursula M Beetles, Miriam A Griffiths, Anil K Jain, Jill Johnson, Rita Roberts, Heather Deans, Karen A Duncan, Geeta Iyengar, Pam M Griffiths, Jane Warwick, Jack Cuzick, Fiona J Gilbert Breast Cancer Research 2008, 10:R64 (23 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Visually assessed breast density can predict breast cancer risk as well as density measured using the ‘gold standard’ labour-intensive interactive threshold software when two views, including the craniocaudal view, are available.
	Research article Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures Pratyaksha Wirapati, Christos Sotiriou, Susanne Kunkel, Pierre Farmer, Sylvain Pradervand, Benjamin Haibe-Kains, Christine Desmedt, Michail Ignatiadis, Thierry Sengstag, Frédéric Schütz, Darlene R Goldstein, Martine Piccart, Mauro Delorenzi Breast Cancer Research 2008, 10:R65 (28 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Breast cancer susceptibility loci and mammographic density Rulla M Tamimi, David Cox, Peter Kraft, Graham A Colditz, Susan E Hankinson, David J Hunter Breast Cancer Research 2008, 10:R66 (5 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer Rulla M Tamimi, Heather J Baer, Jonathan Marotti, Mark Galan, Laurie Galaburda, Yineng Fu, Anne C Deitz, James L Connolly, Stuart J Schnitt, Graham A Colditz, Laura C Collins Breast Cancer Research 2008, 10:R67 (5 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity Sacha J Howell, Elizabeth Anderson, Tom Hunter, Gillian Farnie, Robert B Clarke Breast Cancer Research 2008, 10:R68 (5 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Enrichment with anti-cytokeratin alone or combined with anti-EpCAM antibodies significantly increases the sensitivity for circulating tumor cell detection in metastatic breast cancer patients Glenn Deng, Michael Herrler, David Burgess, Edward Manna, David Krag, Julian F Burke Breast Cancer Research 2008, 10:R69 (7 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3 Christian D Young, Erica C Nolte, Andrew Lewis, Natalie J Serkova, Steven M Anderson Breast Cancer Research 2008, 10:R70 (13 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells Yvonne Radestock, Cuong Hoang-Vu, Sabine Hombach-Klonisch Breast Cancer Research 2008, 10:R71 (21 August 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Variable size computer-aided detection prompts and mammography film reader decisions Fiona J Gilbert, Susan M Astley, Caroline RM Boggis, Magnus A McGee, Pamela M Griffiths, Stephen W Duffy, Olorunsola F Agbaje, Maureen GC Gillan, Mary Wilson, Anil K Jain, Nicola Barr, Ursula M Beetles, Miriam A Griffiths, Jill Johnson, Rita M Roberts, Heather E Deans, Karen A Duncan, Geeta Iyengar Breast Cancer Research 2008, 10:R72 (25 August 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Prompted mammograms, where computer-aided detection systems alert readers to suspicious features, result in more recalls for both normal and cancer cases, and variable size prompts may be most useful.
	Research article A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast cancer Andrew E Teschendorff, Carlos Caldas Breast Cancer Research 2008, 10:R73 (28 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

Explore journal

Articles

Volume 10 Issue 4

Comment

Review

Research