Figure 1.

Cell signalling pathways: targets for breast cancer treatment. EGFR, epidermal growth factor receptor; GPCR, G-protein-coupled receptors; HER, human epidermal growth factor receptor; IKK, inhibitor of NF-κB kinase; mTOR, mammalian target of rapamycin; NF-κB, nuclear factor-κB; TRAIL, tumour necrosis factor-related apoptosis inducing ligand; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor.