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Cross-classification of model A risk decilea × model B risk decileb |
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| Model B risk decile |
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| 1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
Slope |
SE |
P value |
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|
|
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| Model A risk decile |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
Cases/py |
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|
|
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| (Rate) |
(Rate) |
(Rate) |
(Rate) |
(Rate) |
(Rate) |
(Rate) |
(Rate) |
(Rate) |
(Rate) |
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|
|
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| 1 |
41/61,883 |
13/12,253 |
0/756 |
0/20 |
0/2 |
0/0 |
0/0 |
0/0 |
0/0 |
0/0 |
0.471 |
0.318 |
0.14 |
| (66) |
(106) |
(0) |
(0) |
(0) |
(-) |
(-) |
(-) |
(-) |
(-) |
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| 2 |
9/12,317 |
34/42,222 |
36/17,656 |
7/2,535 |
1/187 |
0/6 |
0/0 |
0/0 |
0/0 |
0/0 |
0.593 |
0.129 |
<0.001 |
| (73) |
(81) |
(204) |
(276) |
(535) |
(0) |
(-) |
(-) |
(-) |
(-) |
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| 3 |
0/694 |
9/17,749 |
46/34,208 |
31/18,339 |
8/3,678 |
1/241 |
0/8 |
0/0 |
0/0 |
0/0 |
0.396 |
0.126 |
0.002 |
| (0) |
(51) |
(134) |
(169) |
(218) |
(415) |
(0) |
(-) |
(-) |
(-) |
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| 4 |
0/18 |
1/2,567 |
18/18,588 |
42/31,754 |
43/18,223 |
13/3,547 |
1/217 |
0/6 |
0/0 |
0/0 |
0.48 |
0.102 |
<0.001 |
| (0) |
(39) |
(97) |
(132) |
(236) |
(367) |
(461) |
(0) |
(-) |
(-) |
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| 5 |
0/0 |
0/132 |
5/3,477 |
13/18,417 |
47/31,547 |
50/18,268 |
18/3,010 |
2/158 |
0/0 |
0/0 |
0.565 |
0.085 |
<0.001 |
| (-) |
(0) |
(144) |
(71) |
(149) |
(274) |
(598) |
(1,000) |
(-) |
(-) |
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| 6 |
0/0 |
0/2 |
1/231 |
3/3,635 |
21/18,333 |
50/32,782 |
54/17,504 |
13/2,363 |
0/70 |
0/0 |
0.469 |
0.088 |
<0.001 |
| (-) |
(0) |
(433) |
(83) |
(68) |
(153) |
(309) |
(550) |
(0) |
(-) |
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| 7 |
0/0 |
0/0 |
0/2 |
0/210 |
2/2,922 |
22/17,752 |
76/35,260 |
46/17,428 |
9/1,351 |
0/0 |
0.44 |
0.099 |
<0.001 |
| (-) |
(-) |
(0) |
(0) |
(68) |
(124) |
(216) |
(264) |
(666) |
(-) |
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| 8 |
0/0 |
0/0 |
0/0 |
0/10 |
0/116 |
4/2,272 |
31/17,599 |
87/35,817 |
79/16,063 |
1/339 |
0.5 |
0.091 |
<0.001 |
| (-) |
(-) |
(-) |
(0) |
(0) |
(176) |
(176) |
(226) |
(492) |
(295) |
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| 9 |
0/0 |
0/0 |
0/0 |
0/0 |
0/0 |
0/52 |
4/1,326 |
25/16,137 |
140/46,314 |
65/11,093 |
0.553 |
0.099 |
<0.001 |
| (-) |
(-) |
(-) |
(-) |
(-) |
(0) |
(302) |
(155) |
(302) |
(586) |
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| 10 |
0/0 |
0/0 |
0/0 |
0/0 |
0/0 |
0/0 |
0/0 |
1/305 |
21/11,127 |
315/63,483 |
0.841 |
0.207 |
<0.001 |
| (-) |
(-) |
(-) |
(-) |
(-) |
(-) |
(-) |
(328) |
(189) |
(496) |
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| Overall |
0.511 |
0.034 |
<0.001 |
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aModel A, standard risk prediction model without estradiol. bModel B, standard risk prediction model plus imputed estradiol. py, person-years; SE, standard error. | |||||||||||||
Rosner et al. Breast Cancer Research 2008 10:R55 doi:10.1186/bcr2110 |
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