Table 1 |
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|
Characteristics of the breast cancer cases and controls |
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| Variable |
Cases (n = 648) |
Controls (n = 659) |
P diffa |
|
|
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| Age at blood draw (years; mean ± SD) |
69.2 (5.8) |
69.3 (5.76) |
P = 0.93 |
| Age at diagnosis (years; mean ± SD) |
68.9 (6.25) |
- |
- |
| BMI (kg/m2; mean ± SD) |
25.2 (4.54) |
25.5 (4.56) |
P = 0.22 |
| Adult weight change (lb; mean ± SD) |
27.9 (25.65) |
27.1 (25.91) |
P = 0.58 |
| Race (n [%]) |
|||
| White |
642 (99.1) |
653 (99.1) |
P = 0.98 |
| Other |
6 (0.9) |
6 (0.9) |
|
| BMI (kg/m2; n [%]) |
|||
| <25 |
364 (56.2) |
338 (51.3) |
P = 0.16 |
| 25–30 |
170 (26.2) |
210 (31.9) |
|
| 30+ |
106 (16.4) |
103 (15.6) |
|
| Missing |
8 (1.2) |
8 (1.2) |
|
| History of breast cysts (n [%]) |
|||
| No |
402 (62) |
460 (69.8) |
P = 0.003 |
| Yes |
246 (38) |
199 (30.2) |
|
| Postmenopausal hormone use (n [%]) |
|||
| Never |
213 (32.9) |
255 (38.7) |
P < 0.0001 |
| ERT |
204 (31.5) |
260 (39.5) |
|
| CHRT |
203 (31.3) |
120 (18.2) |
|
| Unknown |
28 (4.3) |
24 (3.6) |
|
| Family history of breast cancer (n [%]) |
|||
| No |
513 (79.2) |
564 (85.6) |
P = 0.002 |
| Yes |
135 (20.8) |
95 (14.4) |
|
| Education (n [%]) |
|||
| <High school |
7 (1.1) |
25 (3.8) |
P = 0.0008 |
| High school |
166 (25.6) |
196 (29.7) |
|
| Some college |
181 (27.9) |
190 (28.8) |
|
| College + |
294 (45.4) |
248 (37.6) |
|
| Age at menopause (years; n [%]) |
|||
| <40 |
55 (8.5) |
72 (10.9) |
P = 0.002 |
| 40 to 44 |
65 (10) |
85 (12.9) |
|
| 45 to 49 |
139 (21.5) |
179 (27.2) |
|
| 50 to 54 |
301 (46.5) |
258 (39.2) |
|
| 55+ |
88 (13.6) |
65 (9.9) |
|
|
|
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|
aP value is a t-test for the means, and a Pearson χ2 for the frequencies. BMI, body mass index; CHRT, combined hormone replacement therapy; ERT, estrogen replacement therapy; SD, standard deviation. |
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|
Feigelson et al. Breast Cancer Research 2008 10:R57 doi:10.1186/bcr2114 |
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