Table 6 |
||||
|
Summary of family characteristics and pathological characteristics of breast cancers of individuals with deleterious BRCA1 and BRCA2 mutations |
||||
| Overall |
BRCA1 |
BRCA2 |
Non-BRCA |
|
|
|
||||
| Age of onset |
22 to 78 |
28 to 57 |
34 to 59 |
22 to 78 |
| Average age of onset (years) |
41.9 |
40.3 |
43.6 |
44.2 |
| Total no. of breast and ovarian cancers in family |
1 to 7 |
1 to 7 |
1 to 7 |
1 to 6 |
| Average no. of breast and ovarian cancers in family |
1.9 |
2.7 |
2.6 |
1.8 |
| No. of cases of breast cancer <50 |
0 to 4 |
1 to 3 |
1 to 3 |
0 to 4 |
| Average no. of cases of breast cancer <50 |
1.1 |
1.6 |
1.5 |
1.0 |
| % with ER-negative tumours |
48% |
100% |
40% |
45% |
|
|
||||
|
Thirthagiri et al. Breast Cancer Research 2008 10:R59 doi:10.1186/bcr2118 |
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