|
Likelihood of having a BRCA1 or BRCA2 deleterious mutations |
||||||
| Personal history |
Family history |
Total |
BRCA1 positive |
BRCA2 positive |
BRCA positive |
BRCA positive |
|
|
||||||
| Number |
Number |
Number |
% |
|||
|
|
||||||
| Breast cancer <50 years |
Nil |
61 |
2 |
3 |
5 |
8.2 |
| Breast cancer <50 years |
1 breast cancer <50 years |
29 |
1 |
3 |
4 |
13.8 |
| Breast cancer ≥ 50 years |
1 breast cancer <50 years |
13 |
1 |
0 |
1 |
7.7 |
| Breast cancer at any age |
≥ 2 breast cancer <50 years |
7 |
1 |
0 |
1 |
14.3 |
| Breast cancer at any age |
≥ 3 breast cancer at any age |
9 |
0 |
3 |
3 |
33.3 |
| Breast cancer at any age |
≥ 1 ovarian cancer at any age |
10 |
4 |
1 |
5 |
50.0 |
| Breast and ovarian cancer |
Any |
5 |
2 |
1 |
3 |
60.0 |
| Bilateral breast cancer |
Any |
25 |
4 |
1 |
5 |
20.0 |
Thirthagiri et al. Breast Cancer Research 2008 10:R59 doi:10.1186/bcr2118 |
||||||