Survival analysis of groups based on module scores. Kaplan-Meier analysis for distant relapse-free survival (DRFS) of systemically untreated (a) and treated (b) patient groups. The ER+ subgroup is split into ER+/HER2-/L and ER+/HER2-/H (low and high proliferation, respectively). Vertical bars on the curves are 95% confidence intervals for the Kaplan-Meier survival estimates. Forest plot representation of the 5-year survival estimates and hazard ratios for DRFS of individual datasets in the systemically untreated (c) and treated (d) populations. The length of horizontal bars and the width of the diamonds of the 'Total' correspond to 95% confidence intervals. Missing bars are unavailable data. Multivariate analysis representation in which all the variables are available in systemically untreated (e) and treated (f) patients. ER, estrogen receptor; HR, hazard ratio.
Wirapati et al. Breast Cancer Research 2008 10:R65 doi:10.1186/bcr2124