|
Age and age-standardised characteristics of breast cancer cases, Nurses' Health Study (1976 to 1996) |
||
| Risk factors |
DCIS (n = 272) |
Invasive (n = 2249) |
|
|
||
| Means |
||
| Age at diagnosis, y |
57.9 |
57.3 |
| Age at menopause, y |
45.2 |
45.5 |
| Age at menarche, y |
12.3 |
12.4 |
| Body mass index at age 18, kg/m2 |
20.9 |
21.0 |
| Paritya |
3.1 |
3.2 |
| Age at first birtha, y |
24.9 |
25.4 |
| Alcohol, g/week |
5.7 |
6.3 |
| Frequency, % |
||
| Family history of breast cancer |
19.0 |
13.3 |
| Nulliparous |
6.9 |
6.9 |
| Premenopausal at diagnosis |
22.4 |
20.8 |
| Postmenopausal at diagnosis |
76.2 |
77.2 |
| Prior benign breast disease |
57.0 |
44.8 |
| Current postmenopausal hormone useb |
37.3 |
31.9 |
| Molecular Markers, % |
||
| ER positive |
74.0 |
77.0 |
| PR positive |
59.9 |
64.4 |
| HER2 positive |
27.2 |
10.9 |
|
aAmong parous women only. bAmong postmenopausal women only. DCIS, ductal carcinoma in situ; ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; PR, progesterone receptor. | ||
Tamimi et al. Breast Cancer Research 2008 10:R67 doi:10.1186/bcr2128 |
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