Table 4 |
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|
Frequency of molecular phenotypes among DCIS and invasive breast cancers, Nurses' Health Study (1976 to 1996) |
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| Immunophenotype |
DCIS (n = 272) |
All invasive (n = 2249) |
Infiltrating ductal, NOS only (n = 1550) |
p valuea |
p valueb |
|
|
|||||
| n (%) |
n (%) |
N (%) |
|||
| Luminal A |
170 (62.5) |
1650 (73.4) |
1053 (67.9) |
0.0002 |
0.08 |
| Luminal B |
36 (13.2) |
116 (5.2) |
90 (5.8) |
<0.0001 |
<0.0001 |
| HER2+ |
37 (13.6) |
128 (5.7) |
107 (6.9) |
<0.0001 |
<0.0001 |
| Basal-like |
21 (7.7) |
245 (10.9) |
223 (14.4) |
0.15 |
0.005 |
| Unclassified |
8 (2.9) |
110 (4.9) |
77 (5.0) |
0.15 |
0.14 |
|
|
|||||
|
ap value from Chi-Squared test comparing DCIS to all invasive tumours. bp value from Chi-Squared test comparing DCIS to infiltrating ductal tumours. DCIS, ductal carcinoma in situ. |
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|
Tamimi et al. Breast Cancer Research 2008 10:R67 doi:10.1186/bcr2128 |
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