Table 5 |
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|
Frequency of molecular phenotypes among DCIS and invasive breast cancers according to tumour gradea, Nurses' Health Study (1976 to 1996) |
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| Tumour type |
Luminal A |
Luminal B |
Her2 type |
Basal |
Unclassified |
|
|
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| DCIS |
|||||
| DCIS, low nuclear grade |
26 (92.9) |
1 (3.6) |
0 |
1 (3.6) |
0 |
| DCIS, intermediate grade |
109 (79.0) |
15 (10.9) |
6 (4.4) |
6 (4.4) |
2 (1.5) |
| DCIS, high nuclear grade |
35 (33.0) |
20 (18.9) |
31 (29.3) |
14 (13.2) |
6 (5.7) |
| Invasive tumours |
|||||
| Well-differentiated |
134 (95.7) |
2 (1.4) |
0 |
2 (1.4) |
2 (1.4) |
| Moderately differentiated |
344 (79.3) |
24 (5.5) |
21 (4.8) |
31 (7.1) |
14 (3.2) |
| Poorly differentiated |
252 (56.8) |
20 (4.5) |
43 (9.7) |
99 (22.3) |
30(6.8) |
|
|
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|
aGrade of DCIS and invasive tumours as determined by centralised pathology review. DCIS, ductal carcinoma in situ. |
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|
Tamimi et al. Breast Cancer Research 2008 10:R67 doi:10.1186/bcr2128 |
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