Table 6 |
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|
Odds ratios (95% confidence interval) of prognostic factors among invasive breast cancers according to molecular phenotype, Nurses' Health Study (1976 to 1996) |
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| Tumour type |
Luminal A |
Luminal B |
Her2 type |
Basal |
Unclassified |
|||||
|
|
||||||||||
| n |
OR |
n |
OR (95%CI) |
n |
OR (95%CI) |
n |
OR (95%CI) |
n |
OR (95%CI) |
|
| Tumour sizea,b |
||||||||||
| ≤ 2.0 cm |
1025 |
54 |
48 |
107 |
57 |
|||||
| >2.0 cm |
537 |
1.0 (Ref) |
55 |
1.9 (1.3 to 2.8) |
68 |
2.6 (1.8 to 3.9) |
119 |
2.0 (1.5 to 2.7) |
44 |
1.4 (0.9 to 2.1) |
| Tumour gradea |
||||||||||
| Low/Intermediate |
478 |
26 |
21 |
33 |
16 |
|||||
| High |
252 |
1.0 (Ref) |
20 |
1.4 (0.8 to 2.6) |
43 |
3.6 (2.1 to 6.3) |
99 |
5.3 (3.5 to 8.1) |
30 |
3.4 (1.8 to 6.4) |
| Nodal statusa,b |
||||||||||
| No nodes |
1103 |
72 |
61 |
145 |
70 |
|||||
| Any nodes |
547 |
1.0 (Ref) |
44 |
1.2 (0.8 to 1.7) |
67 |
2.1 (1.5 to 3.1) |
100 |
1.3 (1.0 to 1.7) |
40 |
1.1 (0.7 to 1.6) |
| Menopausal status |
||||||||||
| Postmenopausal |
1289 |
76 |
97 |
187 |
83 |
|||||
| Premenopausal |
334 |
1.0 (Ref) |
35 |
1.8 (1.2 to 2.7) |
27 |
1.1 (0.7 to 1.7) |
51 |
1.1 (0.8 to 1.5) |
25 |
1.2 (0.7 to 1.8) |
|
|
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|
aAdjusted for age (five-year categories). bTumour characteristics abstracted from medical pathology reports. CI, confidence interval; OR, odds ratio. |
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|
Tamimi et al. Breast Cancer Research 2008 10:R67 doi:10.1186/bcr2128 |
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