Table 2 |
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|
Comparison of p16INK4a immunohistochemistry and RB1 LOH status |
||||||
|
p16 IHC 0 |
1+ |
2+ |
3+ |
Total |
||
|
|
||||||
|
RB1 LOH |
||||||
|
LOH- |
9 (23.7) |
11 (29.0) |
11 (29.0) |
7 (18.4) |
38 |
|
|
LOH+ |
1 (3.9) |
8 (30.8) |
5 (19.2) |
12 (46.2) |
26 |
|
|
10 |
19 |
16 |
19 |
64 |
p = 0.0369 |
|
|
|
||||||
|
0 = negative, 1+ = weak positive, 2+ = moderate positive, 3+ = strong positive. P-values determined by Chi-square test. IHC = immunohistochemistry; LOH = loss of heterozygosity; RB1 = retinoblastoma. |
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|
Herschkowitz et al. Breast Cancer Research 2008 10:R75 doi:10.1186/bcr2142 |
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