Figure 2.

Typical cytomorphology (nuclear size clearly enlarged, high nuclear to cytoplasmic ratio) and immunophenotype (irregular cytoplasmic staining for cytokeratin, cytokeratin filaments can be seen) of a representative disseminated tumour cell from a breast cancer patient. The tumour cell is stained with an anti-cytokeratin-fluorescein isothiocyanate (green) (×40 oil immersion objective).