|
Comparison of ERα status of the primary tumour and metastatic lesion§ |
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| Author |
N |
Primary tumour ER + % |
ER discordance rate (%) |
Site of metastasis |
Change ER+/ER- N (%) |
Change ER-/ER+ N (%) |
|
|
||||||
| Nomura et al. [35] |
42 |
64 |
10 (24) |
LR |
10 (24) |
0 |
| Kuukasjarvi et al. [25] |
50 |
70 |
12 (24) |
LR, MET |
12 (24) |
0 |
| Lower et al. [36] |
200 |
58 |
60 (30) |
MET |
39 (20) |
21 (11) |
| Li et al. [37] |
83 |
76 |
24 (29) |
LR, MET |
83 (16) |
11 (13) |
| Fernandez et al. [27] |
26 |
65 |
(35) |
LN |
6 (23) |
0 |
| Raemaekers et al. [38] |
75 |
58 |
14 (19) |
LR, LN |
8 (10) |
6 (8) |
| Zheng et al. [26] |
52 |
54 |
(10) |
LN |
3 (10) |
0 |
| Ditsch et al. [16] |
17 |
64 |
9 (53) |
DTC |
9 (53) |
0 |
| Broom et al. [28] |
62 |
18 |
11 (18) |
DTC, LN, MET |
6 (10) |
5 (8) |
| Our study |
107 |
82 |
77 (82) |
BM |
76 (71) |
1 (1) |
|
§distant metastasis, local recurrence, lymph nodes BM = bone marrow; DTC = disseminated tumour cells; LN = lymph nodes; LR = local recurrence; MET = metastatic lesion. | ||||||
Fehm et al. Breast Cancer Research 2008 10:R76 doi:10.1186/bcr2143 |
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