Table 2

Distribution of background, tumor characteristics, and recent mammography in relation to use of menopausal hormone therapy

Never use

Past use

Current use

Missing


Total

1,788

253

523

96

Age at diagnosis

50 to 54 years

154 (9)

23 (9)

148 (28)

20

55 to 59 years

320 (18)

45 (18)

181 (35)

32

60 to 64 years

381 (21)

54 (21)

116 (22)

19

65 to 69 years

521 (29)

70 (28)

55 (11)

15

70 to 74 years

412 (23)

61 (24)

23 (4)

10

P valuea

0.99

<0.0001

Socioeconomic statusb

Low

961 (54)

120 (47)

197 (38)

57

High

811 (46)

133 (53)

325 (62)

39

Missing

16

0

1

0

P valuea

0.042

<0.0001

Recent mammography

Yes

933 (59)

147 (64)

361 (73)

61

No

650 (41)

83 (36)

133 (27)

29

Missing

205

23

29

6

P valuea

0.15

<0.0001

Tumor size

≤ 10 mm

488 (28)

59 (24)

151 (29)

30

11 to 20 mm

759 (43)

115 (46)

240 (46)

39

21 to 50 mm

471 (27)

72 (29)

120 (23)

26

>50 mm

56 (3)

3 (1)

10 (2)

1

Missing

14

4

2

0

P valuea

0.17

0.15

Lymph node involvement

0 lymph nodes

1,164 (68)

164 (67)

353 (69)

69

1 to 3 lymph nodes

362 (21)

53 (22)

113 (22)

18

>3 lymph nodes

187 (11)

29 (12)

46 (9)

7

Missing

75

7

11

2

P valuea

0.90

0.44

Mean number of examined lymph nodes

10.4

10.8

10.7

Grade

1

164 (14)

17 (10)

78 (23)

13

2

524 (43)

65 (40)

133 (39)

20

3

520 (43)

81 (50)

130 (38)

33

Missing

580

90

182

30

P valuea

0.23

0.0002

Histology

Ductal

1,314 (74)

180 (72)

338 (66)

69

Lobular

186 (11)

31 (12)

81 (16)

11

Other

269 (15)

38 (15)

93 (18)

15

Missing

19

4

11

1

P valuea

0.64

0.0004

Estrogen receptor (ER), progesterone receptor (PR) status

ER-PR-

227 (18)

37 (19)

55 (15)

17

ER+PR-

200 (16)

32 (17)

40 (11)

14

ER-PR+

42 (3)

5 (3)

23 (6)

2

ER+PR+

776 (62)

116 (61)

240 (67)

40

Missing

543

63

165

23

P valuea

0.91

0.0044


Data presented as n (%). Past use, last use at least 6 months before diagnosis; current use, last use <6 months before diagnosis. aTwo-sided global chi-squared P value for past use and current use, respectively, compared with no use of menopausal hormone therapy. bLow level includes blue-collar workers and low-level white-collar workers, whereas high level includes all other categories.

Rosenberg et al. Breast Cancer Research 2008 10:R78   doi:10.1186/bcr2145

Open Data