Table 2 |
||||
|
Distribution of Chk1 staining category according to clinico-pathological parameters |
||||
| Chk1 fraction positive nuclei (%) |
||||
| Variable |
0 to 5 (n = 108) |
6 to 50 (n = 192) |
51 to 100 (n = 41) |
P value |
|
|
||||
| Tumor type |
0.001a |
|||
| Ductal |
94 |
168 |
32 |
|
| Lobular |
10 |
3 |
2 |
|
| Medullary |
1 |
15 |
6 |
|
| Missing cases: 169 |
||||
| Tumor size (mm) |
0.012b |
|||
| ≥20 |
48 |
64 |
10 |
|
| >20 |
60 |
127 |
31 |
|
| Missing cases: 160 |
||||
| Lymph node status |
0.131b |
|||
| Negative |
24 |
54 |
14 |
|
| Positive |
83 |
138 |
27 |
|
| Missing cases: 160 |
||||
| NHG |
<0.001c |
|||
| I |
18 |
14 |
0 |
|
| II |
67 |
66 |
3 |
|
| III |
20 |
106 |
36 |
|
| Missing cases: 170 |
||||
| Ki67 positive (%) |
<0.001c |
|||
| 0 to 10 |
70 |
55 |
2 |
|
| 11 to 25 |
19 |
61 |
5 |
|
| 26 to 100 |
10 |
52 |
32 |
|
| Missing cases: 194 |
||||
|
|
||||
|
aKruskal-Wallis test (two-sided). bMann-Whitney test (two-sided). cSpearman's ρ. Chk1, checkpoint kinase 1; NHG, Nottingham Histological Grade. |
||||
|
Lundgren et al. Breast Cancer Research 2008 10:R81 doi:10.1186/bcr2150 |
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