Table 2 |
||||
|
Distribution of Chk1 staining category according to clinico-pathological parameters |
||||
|
Chk1 fraction positive nuclei (%) |
||||
|
Variable |
0 to 5 (n = 108) |
6 to 50 (n = 192) |
51 to 100 (n = 41) |
P value |
|
|
||||
|
Tumor type |
0.001a |
|||
|
Ductal |
94 |
168 |
32 |
|
|
Lobular |
10 |
3 |
2 |
|
|
Medullary |
1 |
15 |
6 |
|
|
Missing cases: 169 |
||||
|
Tumor size (mm) |
0.012b |
|||
|
≥20 |
48 |
64 |
10 |
|
|
>20 |
60 |
127 |
31 |
|
|
Missing cases: 160 |
||||
|
Lymph node status |
0.131b |
|||
|
Negative |
24 |
54 |
14 |
|
|
Positive |
83 |
138 |
27 |
|
|
Missing cases: 160 |
||||
|
NHG |
<0.001c |
|||
|
I |
18 |
14 |
0 |
|
|
II |
67 |
66 |
3 |
|
|
III |
20 |
106 |
36 |
|
|
Missing cases: 170 |
||||
|
Ki67 positive (%) |
<0.001c |
|||
|
0 to 10 |
70 |
55 |
2 |
|
|
11 to 25 |
19 |
61 |
5 |
|
|
26 to 100 |
10 |
52 |
32 |
|
|
Missing cases: 194 |
||||
|
|
||||
|
aKruskal-Wallis test (two-sided). bMann-Whitney test (two-sided). cSpearman's ρ. Chk1, checkpoint kinase 1; NHG, Nottingham Histological Grade. |
||||
|
Lundgren et al. Breast Cancer Research 2008 10:R81 doi:10.1186/bcr2150 |
||||
