Table 2

Distribution of Chk1 staining category according to clinico-pathological parameters

Chk1 fraction positive nuclei (%)

Variable

0 to 5 (n = 108)

6 to 50 (n = 192)

51 to 100 (n = 41)

P value


Tumor type

0.001a

Ductal

94

168

32

Lobular

10

3

2

Medullary

1

15

6

Missing cases: 169

Tumor size (mm)

0.012b

≥20

48

64

10

>20

60

127

31

Missing cases: 160

Lymph node status

0.131b

Negative

24

54

14

Positive

83

138

27

Missing cases: 160

NHG

<0.001c

I

18

14

0

II

67

66

3

III

20

106

36

Missing cases: 170

Ki67 positive (%)

<0.001c

0 to 10

70

55

2

11 to 25

19

61

5

26 to 100

10

52

32

Missing cases: 194


aKruskal-Wallis test (two-sided). bMann-Whitney test (two-sided). cSpearman's ρ. Chk1, checkpoint kinase 1; NHG, Nottingham Histological Grade.

Lundgren et al. Breast Cancer Research 2008 10:R81   doi:10.1186/bcr2150

Open Data