Table 3

Immunohistochemical analysis of DKK3 protein expression in breast cancer samples (n = 16) in relation to clinicopathological parameters
Age
 Size1 (pT)
 Node status1 (pN)
 Grade
 Histology
 ER2
 PR2
 DKK3 methylation
 DKK3 IRS tumour3
 DKK3 IRS normal4
49
 1
 0
 3
 IDC
 -
 -
 -
 9
 12
85
 2
 1
 3
 IDC
 -
 -
 n.a.
 3
 n.a.
69
 2
 1
 2
 ILC
 -
 -
 -
 9
 12
82
 3
 1
 3
 IDC
 -
 -
 +
 6
 n.a.
45
 1
 1
 3
 IDC
 -
 -
 +
 4
 12
60
 3
 0
 3
 IDC
 -
 -
 n.a.
 8
 n.a.
61
 1
 0
 2
 IDC
 -
 -
 +
 0
 n.a.
72
 1
 0
 2
 IDC
 -
 -
 n.a.
 4
 n.a.
44
 1
 1
 3
 IDC
 -
 -
 -
 12
 12
86
 2
 n.a.
 3
 IDC
 -
 -
 -
 8
 n.a.
60
 1
 1
 3
 IDC
 +
 -
 +
 2
 9
66
 1
 0
 2
 IDC
 +
 +
 +
 3
 n.a.
54
 2
 0
 3
 IDC
 +
 -
 +
 6
 12
83
 1
 0
 2
 IDC
 +
 +
 -
 9
 n.a.
79
 2
 0
 3
 IDC
 +
 +
 -
 8
 12
62
 4
 1
 3
 IDC
 +
 -
 +
 3
 9

1According to International Union Against Cancer: TNM Classification of Malignant Tumours [32]. 2According to Remmele and Stegner [35]. 3According to Remmele and Stegner [35] as a continuous variable. 4Matched normal breast epithelial tissue. IRS = immunoreactivity score. IDC = invasive ductal carcinoma. ILC = invasive lobular carcinoma. n.a. = not available.

Veeck et al. Breast Cancer Research 2008 10:R82   doi:10.1186/bcr2151