Table 5 |
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Genes selected for quantitative RT-PCR experiments using an independent sample set of in situ component of DCIS/IDC (11 samples) |
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|
Gene symbol |
Microarray (fold change) |
Quantitative RT-PCR (fold change) |
|
|
|
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|
Target genes |
C16orf5 |
5.5 |
1.4 |
|
|
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|
GOSR2 |
4.0 |
6.4a |
|
|
|
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|
LOX |
-2.0 |
-3.6a |
|
|
|
|||
|
SULF-1 |
-4.0 |
-37a |
|
|
|
|||
|
TXNL2 |
4.2 |
-13.4 |
|
|
|
|||
|
Positive and negative numbers indicate upregulated and downregulated genes in pure DCIS, respectively. aGenes confirmed using both methodologies. DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma. |
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|
Castro et al. Breast Cancer Research 2008 10:R87 doi:10.1186/bcr2157 |
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