Table 5

Genes selected for quantitative RT-PCR experiments using an independent sample set of in situ component of DCIS/IDC (11 samples)

Gene symbol

Microarray (fold change)

Quantitative RT-PCR (fold change)


Target genes

C16orf5

5.5

1.4


GOSR2

4.0

6.4a


LOX

-2.0

-3.6a


SULF-1

-4.0

-37a


TXNL2

4.2

-13.4


Positive and negative numbers indicate upregulated and downregulated genes in pure DCIS, respectively. aGenes confirmed using both methodologies. DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma.

Castro et al. Breast Cancer Research 2008 10:R87   doi:10.1186/bcr2157

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