Table 8 |
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|
Univariate and multivariate analysis of the six genes in relation to RFS among the 33 breast cancer samples from the independent cohort (Centre Léon Bérard, Lyon, France) |
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|
Genes |
Univariate (n = 33) |
Multivariate (n = 33) |
||||
|
|
|
|||||
|
HR |
95% CI |
Pa |
HR |
95% CI |
Pa |
|
|
|
||||||
|
ESR1 |
0.12 |
0.04 to 0.36 |
<10-4 |
NS |
||
|
FOS |
0.20 |
0.08 to 0.51 |
<10-4 |
0.15 |
0.03 to 0.89 |
0.038 |
|
BCL2 |
0.08 |
0.02 to 0.24 |
<10-4 |
0.10 |
0.03 to 0.34 |
<10-4 |
|
SNCG |
0.46 |
0.19 to 1.11 |
NS |
NDb |
ND |
ND |
|
IGFBP4 |
0.46 |
0.19 to 1.12 |
NS |
ND |
ND |
ND |
|
MET |
1.38 |
0.60 to 3.21 |
NS |
ND |
ND |
ND |
|
|
||||||
|
aP value was considered significant when P < 0.05. bND indicates 'not done'; multivariate analysis was done using the variables found to be significant in univariate analysis. CI, confidence interval; HR, hazard ratio; NS, not significant; RFS, relapse-free survival. |
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|
Vendrell et al. Breast Cancer Research 2008 10:R88 doi:10.1186/bcr2158 |
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