Research article
Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer
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* Corresponding author: William M Gallagher william.gallagher@ucd.ie
1 UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
2 UCD School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Dublin 4, Ireland
3 Department of Histopathology, Education and Research Centre, The Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland
4 Center for Molecular Pathology, Department of Laboratory Medicine, Malmö University Hospital, Lund University, Malmö, Sweden
5 Department of Pathology and Laboratory Medicine, St Vincent's University Hospital, Dublin 4, Ireland
Breast Cancer Research 2008, 10:R89 doi:10.1186/bcr2187
Published: 23 October 2008Additional files
Additional file 1:
Word file containing a detailed description of each step of the automated image analysis approach used to quantify the ER and PR status.
Format: DOC Size: 34KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional file 2:
Adobe file containing figures outlining the algorithm.
Format: PDF Size: 774KB Download file
This file can be viewed with: Adobe Acrobat Reader