Figure 7.

Quantitative reverse transcriptase (RT) PCR for matrix metalloproteinase (MMP) 2 and MMP9 expression in the index case. RNA was extracted from macrodissected lobular carcinoma in situ (LCIS), adjacent normal (AN) and contralateral normal (CN) lobules. Quantitative RT-PCR for MMP2, MMP9 and the housekeeping gene (GAPDH) was performed. Note the increased expression of MMP9 but not MMP2 in the LCIS versus the normal duct epithelial samples.