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Volume 10 Issue 6
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Comment |
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PGRMC1: a new biomarker for the estrogen receptor in breast cancer
Rolf J Craven Breast Cancer Research 2008, 10:113 (24 November 2008)
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Putative growth characteristics of micrometastatic breast cancer
Ann F Chambers, Paul E Goss Breast Cancer Research 2008, 10:114 (27 November 2008)
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Approaches towards expression profiling the response to treatment
Andrew H Sims, John MS Bartlett Breast Cancer Research 2008, 10:115 (8 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Osteopontin: a new role for a familiar actor
Nicholas IF Johnston, Mohamed K El-Tanani Breast Cancer Research 2008, 10:306 (1 December 2008)
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Review |
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Local control by radiotherapy: is that all there is?
Silvia C Formenti, Sandra Demaria Breast Cancer Research 2008, 10:215 (5 November 2008)
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Genetic counselling and testing for inherited gene mutations in newly diagnosed patients with breast cancer: a review of the existing literature and a proposed research agenda
Bettina Meiser, Kathy Tucker, Michael Friedlander, Kristine Barlow-Stewart, Elizabeth Lobb, Christobel Saunders, Gillian Mitchell Breast Cancer Research 2008, 10:216 (28 November 2008)
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Eph receptors in breast cancer: roles in tumor promotion and tumor suppression
David Vaught, Dana M Brantley-Sieders, Jin Chen Breast Cancer Research 2008, 10:217 (22 December 2008)
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Research |
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A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the Proliferation, Immune response and RNA splicing modules in breast cancer
Fabien Reyal, Martin H van Vliet, Nicola J Armstrong, Hugo M Horlings, Karin E de Visser, Marlen Kok, Andrew E Teschendorff, Stella Mook, Laura van 't Veer, Carlos Caldas, Remy J Salmon, Marc Vijver, Lodewyk FA Wessels Breast Cancer Research 2008, 10:R93 (13 November 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation
Christian Perotti, Ruixuan Liu, Christine T Parusel, Nadine Böcher, Jörg Schultz, Peer Bork, Edith Pfitzner, Bernd Groner, Carrie S Shemanko Breast Cancer Research 2008, 10:R94 (13 November 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines
XingWu Zhu, Lori A Mulcahy, Rabab AA Mohammed, Andrew HS Lee, Hester A Franks, Laura Kilpatrick, Acelya Yilmazer, E Claire Paish, Ian O Ellis, Poulam M Patel, Andrew M Jackson Breast Cancer Research 2008, 10:R95 (17 November 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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ErbB3 is required for ductal morphogenesis in the mouse mammary gland
Amy J Jackson-Fisher, Gary Bellinger, Jerrica L Breindel, Fatteneh A Tavassoli, Carmen J Booth, James K Duong, David F Stern Breast Cancer Research 2008, 10:R96 (18 November 2008)
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A functional Notch–survivin gene signature in basal breast cancer
Connie W Lee, Karl Simin, Qin Liu, Janet Plescia, Minakshi Guha, Ashraf Khan, Chung-Cheng Hsieh, Dario C Altieri Breast Cancer Research 2008, 10:R97 (24 November 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Notch-1-survivin functional gene signature validation as a basal breast cancer hallmark suggests novel roles for Notch and survivin antagonists as molecular therapies against this recurrence-prone disease type.
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Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies
Linda E Kelemen, Fergus J Couch, Shahana Ahmed, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, Zachary S Fredericksen, Robert A Vierkant, V Shane Pankratz, Ellen L Goode, Christopher G Scott, David N Rider, Xianshu Wang, James R Cerhan, Celine M Vachon Breast Cancer Research 2008, 10:R98 (26 November 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells
Anna L Stratford, Christopher J Fry, Curtis Desilets, Alastair H Davies, Yong Y Cho, Yvonne Li, Zigang Dong, Isabelle M Berquin, Philippe P Roux, Sandra E Dunn Breast Cancer Research 2008, 10:R99 (27 November 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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PAI-1 and functional blockade of SNAI1 in breast cancer cell migration
Elizabeth Fabre-Guillevin, Michel Malo, Amandine Cartier-Michaud, Hector Peinado, Gema Moreno-Bueno, Benoît Vallée, Daniel A Lawrence, José Palacios, Amparo Cano, Georgia Barlovatz-Meimon, Cécile Charrière-Bertrand Breast Cancer Research 2008, 10:R100 (3 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
Bérengère Marty, Virginie Maire, Eléonore Gravier, Guillem Rigaill, Anne Vincent-Salomon, Marion Kappler, Ingrid Lebigot, Fathia Djelti, Audrey Tourdès, Pierre Gestraud, Philippe Hupé, Emmanuel Barillot, Francisco Cruzalegui, Gordon C Tucker, Marc-Henri Stern, Jean-Paul Thiery, John A Hickman, Thierry Dubois Breast Cancer Research 2008, 10:R101 (3 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Digoxin treatment is associated with an increased incidence of breast cancer: a population-based case-control study
Thomas P Ahern, Timothy L Lash, Henrik T Sørensen, Lars Pedersen Breast Cancer Research 2008, 10:R102 (3 December 2008)
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Editor’s summary
A modest increase in breast cancer risk was associated with the use of digoxin, a cardiac glycoside used to treat atrial fibrillation, in a case control study of over 55,000 women.
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Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells
Annabel C Borley, Stephen Hiscox, Julia Gee, Chris Smith, Victoria Shaw, Peter Barrett-Lee, Robert I Nicholson Breast Cancer Research 2008, 10:R103 (4 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Tamoxifen, used to treat ER+ breast cancer, can promote an invasive cell phenotype under conditions of poor cell-cell contact, indicating a role for oestrogen deprivation treatment in these cases.
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Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis
Joan S Lewis-Wambi, Helen R Kim, Chris Wambi, Roshani Patel, Jennifer R Pyle, Andres J Klein-Szanto, V Craig Jordan Breast Cancer Research 2008, 10:R104 (5 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Proteomic analysis of tumor necrosis factor-α resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype
Changhua Zhou, Ashley M Nitschke, Wei Xiong, Qiang Zhang, Yan Tang, Michael Bloch, Steven Elliott, Yun Zhu, Lindsey Bazzone, David Yu, Christopher B Weldon, Rachel Schiff, John A McLachlan, Barbara S Beckman, Thomas E Wiese, Kenneth P Nephew, Bin Shan, Matthew E Burow, Guangdi Wang Breast Cancer Research 2008, 10:R105 (16 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Deoxycholate promotes survival of breast cancer cells by reducing the level of pro-apoptotic ceramide
Kannan Krishnamurthy, Guanghu Wang, Dmitriy Rokhfeld, Erhard Bieberich Breast Cancer Research 2008, 10:R106 (16 December 2008)
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The influence of menstrual risk factors on tumor characteristics and survival in postmenopausal breast cancer
Chantal C Orgéas, Per Hall, Lena U Rosenberg, Kamila Czene Breast Cancer Research 2008, 10:R107 (16 December 2008)
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Editor’s summary
Younger age at menarche is associated with higher-grade breast tumours, increased risk of lymph node metastasis and reduced five-year survival, indicates a population based study of over 2500 women.
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The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer
William Tapper, Victoria Hammond, Sue Gerty, Sarah Ennis, Peter Simmonds, Andrew Collins, the Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH) Steering Group, Diana Eccles Breast Cancer Research 2008, 10:R108 (18 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
Alexandra M Pietersen, Hugo M Horlings, Michael Hauptmann, Anita Langerød, Abderrahim Ajouaou, Paulien Cornelissen-Steijger, Lodewijk F Wessels, Jos Jonkers, Marc Vijver, Maarten van Lohuizen Breast Cancer Research 2008, 10:R109 (19 December 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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