Putative growth characteristics of micrometastatic breast cancer

doi:10.1186/bcr2197

Breast Cancer Research

Volume 10
Issue 6

Viewing options:

Abstract
Full text
PDF (38KB)

Associated material:

Related literature:

Articles citing this article
on Google Scholar
on ISI Web of Science
on PubMed Central
Other articles by authors
on Google Scholar

Chambers AF
Goss PE

on PubMed

Chambers AF
Goss PE
Related articles/pages
on Google

on Google Scholar

on PubMed

Tools:

Post to:

Editorial

Putative growth characteristics of micrometastatic breast cancer

Ann F Chambers¹ and Paul E Goss²

¹London Regional Cancer Program, Commissioners Road East, London, Ontario N6A 4L6, Canada

²Massachusetts General Hospital Cancer Center, Fruit Street, LRH-302, Boston, MA 02114, USA

author email corresponding author email

Breast Cancer Research 2008, 10:114doi:10.1186/bcr2197


Published:	27 November 2008

See related research article by Demicheli et al., http://breast-cancer-research.com/content/10/5/R83

Abstract

The fate of cells that disseminate from a primary breast tumour remains poorly understood. Studies of the kinetics of recurrence in breast cancer patients are raising important questions about the biology of the metastatic process. Where do tumour cells reside once they leave the primary tumour, and what factors influence their dormancy and recurrent growth? Clinical data analyses are leading to hypotheses about the biology of metastasis, dormancy and recurrence. A combined clinical and experimental approach to testing these hypotheses will help to clarify this important issue in breast cancer biology and patient care.