Breast Cancer Research

official impact factor 5.79

Open Access Research article

Deoxycholate promotes survival of breast cancer cells by reducing the level of pro-apoptotic ceramide

Kannan Krishnamurthy1, Guanghu Wang1, Dmitriy Rokhfeld2 and Erhard Bieberich1*

Author Affiliations

1 Institute of Molecular Medicine and Genetics, School of Medicine, Medical College of Georgia, 15th Street, Augusta, GA 30912, USA

2 Student Research and Training (STAR) Program, School of Graduate Studies, Medical College of Georgia, 15th Street, Augusta, GA 30912, USA

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Breast Cancer Research 2008, 10:R106 doi:10.1186/bcr2211

Published: 16 December 2008

Additional files

Additional file 1:

Figures S1 and S2. Figure S1A shows hematoxylin and eosin (H&E) staining of a cryosection of a secondary tumor nodule. Figure S1B shows the single color channels of the tumor section shown in Figure 2B and 2C, stained for CD44, Flk1, Hoechst, and Vybrant CM DiI. Figure S2 shows a schematic representation of the anticipated results of the experiment described in Figure 3. It depicts the fate of labeled cells following the two alternative modes of cell division

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