Breast Cancer Research
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Oral presentationMagnetic resonance imaging of ductal carcinoma in situC Kuhl Department of Radiology, University of Bonn, Germany from Symposium Mammographicum 2008
Lille, France. 6–8 July 2008 Breast Cancer Research 2008,
10(Suppl 3):P8doi:10.1186/bcr2006 The electronic version of this abstract is the complete one and can be found online at: http://breast-cancer-research.com/content/10/S3/P8
©
2008 BioMed Central Ltd Oral presentation
Intraductal cancer or ductal carcinoma in situ (DCIS) has been considered a mammographic disease. Before the advent of mammographic screening, only about 2% to 5% of breast cancers were diagnosed in the intraductal stage. Magnetic resonance imaging (MRI) has traditionally been considered insensitive for DCIS. More recent studies, however, suggest that, with appropriate diagnostic criteria, contrast-enhanced MRI may be a very sensitive tool for diagnosing DCIS, especially high-grade DCIS. In addition, MRI has been shown to be superior to delineate the intraductal extension of invasive cancers – another reason why preoperative staging with MRI is important. The likelihood with which the mammographic diagnosis of DCIS or DCIS components fails does not correlate with mammographic breast density – in other words, a missed mammographic diagnosis of DCIS is also conceivable in women with involuted breast. The present lecture summarizes the current level of evidence, and discusses the clinical implications of these findings.
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