CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

doi:10.1186/bcr2215

Breast Cancer Research

Volume 11
Issue 1

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Zabouo G
Imbert AM
Jacquemier J
Finetti P
Moreau T
Esterni B
Birnbaum D
Bertucci F
Chabannon C

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Zabouo G
Imbert AM
Jacquemier J
Finetti P
Moreau T
Esterni B
Birnbaum D
Bertucci F
Chabannon C
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Research article

CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

Gwladys Zabouo¹^,2 , Anne-Marie Imbert¹^,2 , Jocelyne Jacquemier³^,4 , Pascal Finetti⁴ , Thomas Moreau¹^,2 , Benjamin Esterni² , Daniel Birnbaum⁴ , François Bertucci²^,4^,5^,6 and Christian Chabannon¹^,2^,6^,7

¹Institut Paoli-Calmettes, Centre de Ressources Biologiques en Oncologie, Centre de Thérapie Cellulaire et Génique, Marseille 13009, France

²Inserm U891, Centre de Recherche en Cancérologie de Marseille, Equipe Recherche Clinique, Marseille 13009, France

³Institut Paoli-Calmettes, Département de Bio-pathologie, Marseille 13009, France

⁴Inserm U891, Centre de Recherche en Cancérologie de Marseille, Equipe Oncologie Moléculaire, Marseille 13009, France

⁵Institut Paoli-Calmettes, Département de Médecine, Marseille 13009, France

⁶Université de la Méditerranée, Marseille 13007, France

⁷Inserm CIC-B510, Centre d'Investigations Cliniques en Biothérapie, Marseille 13009, France

author email corresponding author email

Breast Cancer Research 2009, 11:R1doi:10.1186/bcr2215


Published:	5 January 2009

Additional files

Additional file 1:

A Word file containing information about the mAbs used in the present study.

Format: DOC Size: 44KB Download file

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Additional file 2:

A Word file containing information about the sequences of primers used in quantitative RT-PCR and sequences of siRNAs and shRNAs.

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Additional file 3:

A Word file containing a table that presents the genes tested by quantitative RT-PCR.

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Additional file 4:

A Word file containing a table that presents the genes of the stromal cluster.

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Additional file 5:

An Adobe file containing a figure showing the downmodulation of CD146 in MDA-MB-231 cells with shRNAs targeting CD146.

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Additional file 6:

An Adobe file containing a figure showing the mRNA expression levels between the wild-type and the mock-transfected MDA-MB-231 cell lines displayed as a volcano plot.

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