Table 2 |
|||
|
Genes modulated as a consequence of CD146 downmodulation |
|||
|
Symbol |
Accession number |
Fold change |
P value (t test) |
|
|
|||
|
DNA microarray |
|||
|
LIPG |
[GenBank:NM_006033] |
-6.75 |
0.02749 |
|
MCAM |
[GenBank:NM_006500] |
-3.61 |
0.00084 |
|
FPR1 |
[GenBank:NM_002029] |
-2.88 |
0.03159 |
|
CYP1B1 |
[GenBank:NM_000104] |
-2.73 |
0.03208 |
|
FN1 |
[GenBank:NM_212475] |
-2.48 |
0.00657 |
|
SORCS2 |
[GenBank:NM_020777] |
-2.17 |
0.0314 |
|
FLJ20160 |
[GenBank:NM_017694] |
-1.74 |
0.01431 |
|
LTBP1 |
[GenBank:NM_206943] |
-1.72 |
0.03606 |
|
HES1 |
[GenBank:NM_005524] |
-1.7 |
0.04315 |
|
AIM1 |
[GenBank:NM_001624] |
-1.63 |
0.00758 |
|
MFAP2 |
[GenBank:NM_002403] |
-1.58 |
0.04437 |
|
HIPK2 |
[GenBank:NM_022740] |
-1.55 |
0.00781 |
|
CALD1 |
[GenBank:NM_033138] |
-1.51 |
0.0113 |
|
NAV1 |
[GenBank:NM_020443] |
-1.5 |
0.00481 |
|
NFIC |
[GenBank:NM_005597] |
-1.5 |
0.0275 |
|
TGFBI |
[GenBank:NM_000660] |
-1.85* |
0.03459 |
|
TRIM59 |
[GenBank:NM_173084] |
-1.76* |
0.01626 |
|
NFAT5 |
[GenBank:NM_138714] |
-1.51* |
0.04496 |
|
APCDD1L |
[GenBank:NM_153360] |
-2.38** |
0.01035 |
|
GARNL4 |
[GenBank:NM_001100398] |
-1.96** |
0.04209 |
|
PCMTD1 |
[GenBank:NM_052937] |
-1.59** |
0.0362 |
|
Multiplex quantitative RT-PCR |
|||
|
KALRN |
[GenBank:NM_003947] |
-10 |
0.02973 |
|
PREX1 |
[GenBank:NM_020820] |
-8.93 |
0.01711 |
|
VAV1 |
[GenBank:NM_005428] |
-7.94 |
0.00688 |
|
FGD4 |
[GenBank:NM_139241] |
-4.63 |
0.00318 |
|
RHOV |
[GenBank:NM_133639] |
-4.03 |
0.03116 |
|
CCL5 |
[GenBank:NM_002985] |
-3.88 |
0.00536 |
|
ITGB3 |
[GenBank:NM_000212] |
-3.61 |
0.00187 |
|
CXCL16 |
[GenBank:NM_022059] |
-2.92 |
0.00252 |
|
THBS1 |
[GenBank:NM_003246] |
-2.66 |
0.01279 |
|
CXCR4 |
[GenBank:NM_001008540] |
-2.21 |
0.00259 |
|
ITGB4 |
[GenBank:NM_001005731] |
-2.15 |
0.01068 |
|
CD44 |
[GenBank:NM_000610] |
-1.92 |
0.00141 |
|
ITGA2 |
[GenBank:NM_002203] |
-1.86 |
0.00191 |
|
ROCK2 |
[GenBank:NM_004850] |
-1,80 |
0.00004 |
|
ITGA6 |
[GenBank:NM_000210] |
-1.63 |
0.00274 |
|
VIM |
[GenBank:NM_003380] |
-1.45*** |
0.04761 |
|
ARHGEF11 |
[GenBank:NM_198236] |
1.67 |
0.00288 |
|
BCL7A |
[GenBank:NM_001024808] |
1.69 |
0.02473 |
|
DEF6 |
[GenBank:NM_022047] |
2.05 |
0.00946 |
|
TNK2 |
[GenBank:NM_005781] |
2.18 |
0.00222 |
|
CXCL10 |
[GenBank:NM_001565] |
2.51 |
0.03645 |
|
|
|||
|
*Not validated by quantitative RT-PCR. **Quantitative RT-PCR not available.***Observed only with the TI6194 cell line. |
|||
|
Zabouo et al. Breast Cancer Research 2009 11:R1 doi:10.1186/bcr2215 |
|||
