Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression

doi:10.1186/bcr2256

Breast Cancer Research

Volume 11
Issue 3

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Williams C
Helguero L
Edvardsson K
Haldosén LA
Gustafsson J

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Research article

Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression

Cecilia Williams¹^,2 , Luisa Helguero² , Karin Edvardsson¹^,2 , Lars-Arne Haldosén² and Jan-Åke Gustafsson¹^,2

¹Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, 3013 Science & Engineering Research Center, Houston, TX 77204, USA

²Department of Biosciences and Nutrition, Novum, Karolinska Institutet, 141 57 Stockholm, Sweden

author email corresponding author email

Breast Cancer Research 2009, 11:R26doi:10.1186/bcr2256


Published:	8 May 2009

Additional files

Additional data file 1:

Excel file containing a table that lists all differentially expressed genes detected in the microarray analysis. Gene symbol, gene name, GenBank, and changes between the different stages with corresponding statistical values are given in separate columns.

Format: XLS Size: 1.1MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 2:

Adobe file containing a figure that shows the real-time PCR confirmations of differentially expressed genes: confirmation of microarray results and correlating changes in in vivo mammary glands, of genes regulated during differentiation of HC11 cells.

Format: PDF Size: 21KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 3:

Adobe file containing a figure that shows the real-time PCR confirmations of differentially expressed genes: correlating changes in in vivo mammary glands, of genes regulated during differentiation of HC11 cells.

Format: PDF Size: 19KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 4:

Adobe file containing a figure that shows the real-time PCR confirmations of differentially expressed genes: expression of nuclear receptors and/or related genes increasing during HC11 mammary stem-like differentiation and correlating changes in vivo mammary glands.

Format: PDF Size: 17KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 6:

image file containing a figure that shows expression of vimentin analyzed by immunofluorescence in HC11 stem cell-like, pre-differentiated and differentiated cells.

Format: TIFF Size: 8.9MB Download file

Additional data file 7:

image file containing a figure that shows expression of the milk protein beta casein analyzed by immunofluorescence in HC11 stem cell-like, pre-differentiated and differentiated cells.

Format: TIFF Size: 8.9MB Download file

Additional data file 5:

Adobe file containing a figure that shows the real-time PCR confirmations of differentially expressed genes: expression of nuclear receptors and/or related genes decreasing during HC11 mammary stem-like differentiation and correlating changes in vivo mammary glands.

Format: PDF Size: 18KB Download file

This file can be viewed with: Adobe Acrobat Reader