Table 2

Distribution of breast cancer tumor subtypes by race/ethnicity in the combined LACE and Pathways Studies (n = 2544)

Tumor subtype

White n (%)

African American n (%)

Asian n (%)

Hispanic n (%)

Other n (%)

P valuea


Luminal A

(ER+ and/or PR+, Her2-)

n = 1868 (73.4)

1464 (75.3)

92 (59.4)

135 (71.4)

135 (68.5)

37 (68.5)

0.0001

Luminal B

(ER+ and/or PR+, Her2+)

n = 294 (11.6)

215 (11.1)

14 (9.0)

30 (15.9)

28 (14.2)

7 (13.0)

0.18

Triple negative

(ER-, PR-, Her2-)

n = 288 (11.3)

204 (10.5)

44 (28.4)

12 (6.3)

21 (10.7)

7 (13.0)

< 0.0001

Her2 overexpressing

(ER-, PR-, Her2+)

n = 94 (3.7)

60 (3.1)

5 (3.2)

12 (6.4)

13 (6.6)

3 (5.5)

0.03


Total n = 2544 (100)

1943 (100)

155 (100)

189 (100)

197 (100)

54 (100)

---


a From Pearson chi-square test across racial/ethnic categories.

ER = estrogen receptor; Her2 = human epidermal growth receptor 2; PR = progesterone receptor; + = positive; - = negative.

Kwan et al. Breast Cancer Research 2009 11:R31   doi:10.1186/bcr2261

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