Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer

Frank Wiesmann1, Jürgen Veeck2, Oliver Galm3, Arndt Hartmann4, Manel Esteller2, Ruth Knüchel1 and Edgar Dahl1*

Author Affiliations

1 Molecular Oncology Group, Institute of Pathology, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, D-52074 Aachen, Germany

2 Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Institute for Biomedical Research (ICO-IDIBELL), Av. Gran Via de L'Hospitalet 199-203, E-08907 Barcelona, Spain

3 Department of Internal Medicine IV (Haematology/Oncology), University Hospital of the RWTH Aachen, Pauwelsstrasse 30, 52074 D-Aachen, Germany

4 Department of Pathology, University of Erlangen, Krankenhausstrasse 12, D-91054 Erlangen, Germany

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Breast Cancer Research 2009, 11:R34 doi:10.1186/bcr2319

Published: 15 June 2009

Additional files

Additional data file 1:

A PDF file that demonstrates the specificity of the applied EDN3 antibody by use of competitive blocking peptide in immunohistochemistry.

Format: PDF Size: 1.3MB Download file

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Open Data