Table 6

Univariate Cox proportional hazard analysis (disease-free survival) in the oestrogen-receptor-negative cohort

Variable

Evaluation

Hazard ratio (95% confidence interval)

P value

Tumour size

T1 (≤ 2 mm)

1

T2 (2 < T ≤ 5 mm)

1.45 (0.40 to 5.21)

0.567

T3 (>5 mm)

3.57 (0.88 to 14.4)

0.073

Lymph node stage

Negative

1

1 to 3 lymph nodes

0.47 (0.10 to 2.16)

0.338

>3 lymph nodes

2.49 (1.02 to 6.03)

0.044

Tumour grade

Grade I

^a

Grade II

1

Grade III

2.85 (1.05 to 7.57)

0.040

HER-2/neu expression

HER-2/neu-negative

1

HER-2/neu-positive

2.04 (0.90 to 4.61)

0.086

FOXA1 expression

FOXA1-positive

1

FOXA1-negative

3.61 (0.83 to 15.60)

0.086

GATA-3 expression

GATA-3-positive

1

GATA-3-negative

1.53 (0.44 to 5.28)

0.495

FOXA-1, forkhead box A1; GATA-3, GATA binding protein 3; HER-2, human epidermal growth factor receptor 2. ^aThere were no oestrogen-receptor-negative cases classified as grade I among the patients with available follow-up information.

Albergaria et al. Breast Cancer Research 2009 11:R40   doi:10.1186/bcr2327